Steroid Hormones Do Not Reactivate Neospora caninum in Ovariectomized Mice.
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概要
- 論文の詳細を見る
The direct effects of three steroid hormones (progesterone, estradiol-17β and corticosterone) on the growth of Neospora caninum (N. caninum) tachyzoite were examined in Vero cells. Subsequently, ovariectomized BALB/c mice infected with N. caninum were treated with physiological concentrations of the steroid hormones for 1 or 2 weeks. These hormones had no direct effect on the parasite growth in vitro. In the infected mice, there was no significant difference in the parasite distribution and histopathological changes between the hormone-injected and control groups. No mice showed parasitemia at the time of autopsy. These results suggest that physiological levels of steroid hormones (progesterone, estradiol-17β and corticosterone) do not reactivate N. caninum in mice.
- 公益社団法人 日本獣医学会の論文
著者
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Katagiri Seiji
Laboratory Of Theriogenology Department Of Clinical Sciences Graduate School Of Veterinary Medicine
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Ochiai Kenji
Laboratory Of Comparative Pathology Department Of Veterimary Sciences Graduate School Of Veterimary
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Umemura Takashi
Laboratory Of Comparative Pathology Department Of Veterinary Clinical Sciences Graduate School Of Ve
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Kobayashi Atsushi
Laboratory Of Comparative Pathology Department Of Veterinary Clinical Sciences School Of Veterinary
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Kimura Takashi
Laboratory Of Animal Reproduction Faculty Of Agricultural Science Yamagata University
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KOBAYASHI Atsushi
Laboratory of Comparative Pathology, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University
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