Cutaneous Lymphoplasmacytic Lymphoma with Systemic Metastasis in a Cat
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概要
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A lymphoplasmacytic lymphoma was diagnosed in a 12- year-old domestic cat that had a primary cutaneous mass involving the stomach, liver, kidneys, heart, abdominal wall, diaphragm, bone marrow and several lymph nodes. Histopathologically, the most characteristic feature of this tumor was its composition of heterogeneous cells, such as small lymphocytes, well-differentiated plasma cells and plasmacytoid transformed lymphocytes. Amyloid was deposited in the skin, stomach, and several lymph nodes. Immunohistochemically, neoplastic small lymphocytes were positive for CD20, and well-differentiated plasma cells and plasmacytoid transformed lymphocytes were positive for λ-Ig light chains and MUM1/IRF-4. These results emphasize the importance of lymphoplasmacytic lymphoma as a differential diagnosis of extramedullary cutaneous plasmacytoma in cats.
著者
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KAGAWA Yumiko
North Lab
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Taniyama Hiroyuki
Department Of Veterinary Pathology School Of Veterinary Medicine Rakuno Gakuen University
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Umemura Takashi
Laboratory Of Comparative Pathology Department Of Veterinary Clinical Sciences Graduate School Of Ve
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SAKAGUCHI Kanako
Department of Pathology, School of Veterinary Medicine, Rakuno Gakuen University
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Hirayama Kazuko
Department Of Organic Materials National Institute Of Materials And Chemical Research
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YAMASHITA Tokiaki
Makomanai Animal Hospital
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MAETANI Shigeki
Maetani Animal Hospital
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AOKI Yuko
North Lab
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Sakaguchi Kanako
Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University
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TANIYAMA Hiroyuki
Department of Veterinary Pathobiology, Rakuno Gakuen University
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