Extensive Accumulation of Influenza Virus NS1 Protein in the Nuclei Causes Effective Viral Growth in Vero Cells
スポンサーリンク
概要
- 論文の詳細を見る
We previously showed that modified A/Puerto Rico/8/34 (PR8) influenza master strain had improved viral rescue and growth properties in African green monkey kidney (Vero) cell line by introducing NS gene of Vero-adapted A/England/1/53 (vaEng53). In the present study, it was found that the NS1 protein derived from vaEng53 was extensively accumulated in the nuclei than that of PR8. This accumulation was caused by 7 amino acid differences in C-terminal region of NS1 protein. These results suggest that specific accumulation of NS1 protein may contribute to efficient viral replication in Vero cells.
- Center for Academic Publications Japanの論文
- 2007-05-20
著者
-
Kida Hiroshi
Department Of Cardiology Kanazawa National Hospital
-
Ozaki Hiroichi
Creative Research Initiative 'sousei' Hokkaido University
-
Ozaki Hiroichi
Creative Res. Initiative ‘sousei' Hokkaido Univ.
-
Kida Hiroshi
Department Of Disease Control Hokkaido University Graduate School Of Veterinary Medicine
関連論文
- Increase in the Neuraminidase Activity of a Nonpathogenic Newcastle Disease Virus Isolate during Passaging in Chickens
- Protective effects of intranasal vaccination with plasmid encoding pseudorabies virus glycoprotein B in mice
- Antigenic and genetic analyses of H5 influenza viruses isolated from ducks in Asia
- Highly Pathogenic H5N1 Influenza Virus Causes Coagulopathy in Chickens
- Mucosal vaccination against influenza : Protection of pigs immunized with inactivated virus and ether-split vaccine
- ACQUISITION OF PATHOGENICITY OF A NEWCASTLE DISEASE VIRUS ISOLATED FROM A JAPANESE QUAIL BY INTRACEREBRAL PASSAGE IN CHICKENS
- A Low Pathogenic H5N2 Influenza Virus Isolated in Taiwan Acquired High Pathogenicity by Consecutive Passages in Chickens
- Cardiac Sympathetic Nervous System Represses Natriuretic Peptide Release in Humans
- Relationship between plasma homocysteine and coronary stenosis morphology in Japanese patients with coronary artery disease
- Effects of Endoscopic Transthoracic Sympathicotomy on Hemodynamic and Neurohumoral Responses to Exercise in Humans
- Antibodies to Human-Related H3 Influenza A Virus in Baikal Seals (Phoca sibirica) and Ringed Seals (Phoca hispida) in Russia
- Influenza virus infection in seal (Phocidae) : seroepidemiological survey of influenza virus in Caspian seals(Phoca caspica)
- Serological Evidence of Transmission of Human Influenza A and B Viruses to Caspian Seals (Phoca caspica)
- OJ-204 The Course Taken by Sympathetic Efferent Fibers from Th4 Ganglion to The Sinus Node in Humans(Autonomic Nervous System 2 (H) : OJ23)(Oral Presentation (Japanese))
- Prevalence of Migraine and Raynaud's Phenomenon in Japanese Patients With Vasospastic Angina
- Electron-dense deposition patterns and the outcomes of idiopathic membranous nephropathy in Japanese
- Subcutaneous Hematoma Due to Frequent Insulin Injections in a Single Site
- Effect of Endoscopic Transthoracic Sympathicotomy on Plasma Natriuretic Peptide Concentrations in Humans
- Evaluation of the ESPLINE^【○!R】 INFLUENZA A&B-N Kit for the Diagnosis of Avian and Swine Influenza
- VIRAL DISEASES OF LIVESTOCK IN ZAMBIA
- A NEUTRAL SUGAR IS RESPONSIBLE FOR SEROVAR SPECIFICITY OF THE ANTIGENIC DETERMINANT OF LEPTOSPIRA INTERROGANS SEROVAR CANICOLA
- SURVEY OF INFLUENZA VIRUSES IN FERAL BIRDS IN 1979 AND ISOLATION OF A STRAIN POSSESSING Hav6Nav5 FROM CLOACA OF AN EASTERN DUNLIN
- DISTRIBUTION OF ANTIBODIES IN ANIMALS AGAINST INFLUENZA B AND C VIRUSES
- A Rapid and Highly Sensitive Method for Diagnosis of Equine Influenza by Antigen Detection Using Immuno-PCR
- Antigenic Variation Among Equine H 3 N 8 Influenza Virus Hemagglutinins
- THE EFFECTIVENESS OF TRYPSIN TREATMENT TO REMOVE SENDAI VIRUS ADHERING TO THE ZONA PELLUCIDA OF MOUSE PREIMPLANTATION EMBRYOS
- Extensive Accumulation of Influenza Virus NS1 Protein in the Nuclei Causes Effective Viral Growth in Vero Cells
- Effect of Sendai Virus Exposure on the Development of Frozen-Thawed Mouse Embryos
- Serological Evidence of Leptospiral Infection in Pig Populations in Different Districts in Japan
- MUTATION OF GROWTH OF LEPTOSPIRES IN SHENBERG'S MEDIUM
- STUDIES ON CULTURAL AND SEROLOGICAL PROPERTIES AND VIRULENCE OF LEPTOSPIRA
- Favorable response to crizotinib in three patients with echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase fusion-type oncogene-positive non-small cell lung cancer
- Recurrent allergic bronchopulmonary aspergillosis in a patient with rheumatoid arthritis treated with etanercept and tocilizumab
- Two cases of leptomeningeal metastases from lung adenocarcinoma which progressed during gefitinib therapy but responded to erlotinib
- Drug-induced Thrombotic Thrombocytopenic Purpura Successfully Treated with Recombinant Human Soluble Thrombomodulin