Effects of Endoscopic Transthoracic Sympathicotomy on Hemodynamic and Neurohumoral Responses to Exercise in Humans
スポンサーリンク
概要
- 論文の詳細を見る
Endoscopic transthoracic sympathicotomy (ETS) is a minimal invasive procedure of thoracic sympathetic block and has been used successfully in the treatment of primary palmar hyperhidrosis. To examine the effect of Th 2-3 ETS on hemodynamic responses to submaximal upright treadmill exercise in humans, cardiac output, plasma noradrenaline and adrenaline at rest and during the last 40s of stage 2 in a modified Bruce protocol were measured before and after ETS in 21 patients with primary palmar hyperhidrosis. Heart rate, mean arterial pressure, rate-pressure product, and noradrenaline decreased at rest and at submaximal exercise after ETS. Cardiac index at rest did not change either before or after ETS, but decreased (8.9±0.6 vs 6.8±0.4L・min^<-1>・m^<-2>; p<0.01, mean±SEM) at submaximal exercise after ETS. Stroke index and systemic vascular resistance were similar both at rest and at submaximal exercise before and after ETS. Thus, ETS reduces myocardial oxygen demand and plasma noradrenaline levels both at rest and during exercise without significantly depressing cardiac function in terms of stroke volume.
- 社団法人日本循環器学会の論文
- 2002-03-20
著者
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Nagata Yoshiki
Department of Internal Medicine, Toyama Prefectural Central Hospital
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FUJIMOTO Manabu
Department of Dermatology, Kanazawa University Hospital
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Fujimoto Manabu
Department Of Cardiology Kanazawa National Hospital
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KIDA Hiroshi
Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University
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Nakamura Yukio
Department Of Cardiology Kanazawa Medical Center
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Nagata Yoshiki
Department Of Cancer Gene Regulation Gastroenterology And Nephrology Graduate School Of Medical Scie
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Nagata Yoshiki
Departments Of Cardiology National Kanazawa Hospital
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Matsumoto Yasushi
Department Surgery (I), Kanazawa University School of Medicine
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Kida Hiroshi
Department Of Cardiology National Hospital Organization Kanazawa Medical Center
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Yoshizawa Hisashi
Department of Cardiology, National Kanazawa Hospital
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Shiraishi Ko-ichi
Departments of Cardiology, National Kanazawa Hospital
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Nakamura Yukio
Department Of Biotechnology Faculty Of Agriculture Gifu University
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Kida Hiroshi
Department Of Cardiology Kanazawa National Hospital
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Fujimoto Manabu
Departments Of Cardiology National Kanazawa Hospital
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Shiraishi Ko-ichi
Departments Of Cardiology National Kanazawa Hospital
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Nakamura Yukio
Department Of Cardiology Kanazawa National Hospital
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Yoshizawa Hisashi
Department Of Cardiology National Hospital Organization Kanazawa Medical Center
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Matsumoto Yasushi
Department Of Cardiovascular Surgery National Hospital Organization Kanazawa Medical Center
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Matsumoto Yasushi
Department Of Cardiovascular Surgery Kanazawa Medical Center
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NAKAMURA Yukio
Department of Agricultural Chemistry, Faculty of Agriculture, Gifu University
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