Two Peaks in pH Dependence of Renin-angiotensinogen Reaction
スポンサーリンク
概要
- 論文の詳細を見る
The pH dependence of the reaction of purified recombinant human renin with purified recombinant sheep angiotensinogen was not a typical bell-shape but had two peaks, pH 6.4 and 8.9. The pH dependence of the reaction of human renin with human, hog, and rat angiotensinogens partially purified from plasma had a peak with a shoulder containing two peaks close together. These findings indicate that the reaction of renin with angiotensinogen involves at least two amino acid residues other than the two aspartic acid residues known to be involved and occurs at acidic pH and basic pH by two different pairs of these amino acid residues.
- 社団法人日本農芸化学会の論文
- 1998-02-23
著者
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Nakamura Yukio
Department Of Cardiology Kanazawa Medical Center
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Suzuki F
Laboratory Of Animal Biochemistry Faculty Of Applied Biological Science Gifu University
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Suzuki F
Gifu Univ Gifu Jpn
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Suzuki Fumiaki
Department Of Biotechnology Faculty Of Agriculture Gifu University
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Nasir Uddin
United Graduate School Of Agricultural Science Gifu University
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Nakamura Yukio
Department Of Biotechnology Faculty Of Agriculture Gifu University
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Nakagawa Tsutomu
Department of Cardiology, Toyonaka Municipal Hospital
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SUZUKI Fumiaki
Molecular Genetics Research Center Gifu University
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NAGAI Takao
Department of Biotechnology, Faculty of Agriculture Gifu University
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TAKAHASHI Kohji
Department of Biotechnology, Faculty of Agriculture
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Nakagawa Tsuyoshi
Dep. Of Molecular And Functional Genomics Center For Integrated Res. In Sci. Shimane Univ.
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Suzuki Fumiaki
United Graduate School Of Agricultural Science Gifu University
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Takahashi Kohji
Department Of Biotechnology Faculty Of Agriculture
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Takahashi Kohji
Department Of Applied Physics Waseda University
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Nakagawa Tsutomu
Department Of Cardiology Toyonaka Municipal Hospital
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NAKAMURA Yukio
Department of Agricultural Chemistry, Faculty of Agriculture, Gifu University
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