Ren-2 as Well as Ren-1 Renin Exists in the Kidney and Plasma of a Two-renin Gene Mouse(Biological Chemistry)

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概要

• 論文の詳細を見る

• Ren-1 renin is synthesized in the kidney of every mouse. Ren-2 renin has been observed in the submandibular gland (SMG) of male mice carrying two renin genes. However, it is not known if Ren-2 renin is in the kidney and blood of the two-renin gene mice. In this study, a direct ELISA for Ren-2 renin (SMG renin) was established by a sandwich method. This ELISA could measure the Ren-2 active renin in the range from 1 to 100 ng and distinguish Ren-2 active renin from not only Ren-1 renin but also Ren-2 prorenin. By a combination of this assay system and conventional methods, the pro-form as well as the active form of Ren-2 renin was found in the kidney and plasma of male AKR mice carrying two-renin genes.

• 社団法人日本農芸化学会の論文
• 1990-09-23

著者

• Nakamura Yukio

  Department Of Cardiology Kanazawa Medical Center

• Nakamura Y

  Department Of Biotechnology Faculty Of Agriculture Gifu University

• Suzuki F

  Laboratory Of Animal Biochemistry Faculty Of Applied Biological Science Gifu University

• Suzuki F

  Gifu Univ Gifu Jpn

• Suzuki Fumiaki

  Department Of Biotechnology Faculty Of Agriculture Gifu University

• Suzuki Fumiaki

  Department Of Animal Science And Technology Faculty Of Agriculture Gifu University

• Nakamura Y

  Kyoto Univ. Kyoto Jpn

• Nakamura Yukio

  Department Of Biotechnology Faculty Of Agriculture Gifu University

• Yamashita Shinji

  Department Of Electronic Engineering The University Of Tokyo

• Suzuki Fumiaki

  United Graduate School Of Agricultural Science Gifu University

• NAGATA Yukio

  Department of Agricultural Chemistry, Faculty of Agriculture

• Yamashita Shinji

  Department Of Biotechnology Faculty Of Agriculture Gifu University

• Yamashita Shinji

  Department De Mathematique Universite Metropolitaine De Tokyo

• ITO Miki

  Department of Biotechnology, Faculty of Agriculture, Gifu University

• Ito Miki

  Department Of Biotechnology Faculty Of Agriculture Gifu University

• Ito Miki

  Department Of Bioscience And Biotechnology Faculty Of Science And Engineering Ritsumeikan University

• SUZUKI Fumiaki

  Department of Agricultural Chemistry, Faculty of Agriculture, Gifu University

• NAKAMURA Yukio

  Department of Agricultural Chemistry, Faculty of Agriculture, Gifu University

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