Expression and Characterization of Dog CYP2D15 Using Baculovirus Expression System^1
スポンサーリンク
概要
- 論文の詳細を見る
- Japanese Biochemical Societyの論文
- 1998-01-01
著者
-
Iwata H
Laboratory Of Toxicology Department Of Environmental Veterinary Sciences Graduate School Of Veterina
-
Iwata Hisato
北海道大学 獣医研究 環境獣医
-
IWATA Hisato
Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Graduate School of Veteri
-
KAZUSAKA Akio
Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Graduate School of Veteri
-
FUJITA Shoichi
Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Graduate School of Veteri
-
TASAKI Takafumi
Laboratory of Toxicology, Department of Environmental Veterinary Medical Sciences, Graduate School o
-
Masuda Makihiko
Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Graduate School of Veteri
-
Fujita Shoichi
北海道大学 獣医研究 環境獣医
-
NAKAMURA Akio
Laboratory of Chemistry, School of Design and Architecture, Nagoya City University
-
Kazusaka Akio
Laboratory Of Toxicology Department Of Environmental Veterinary Sciences
-
ITOH Susumu
Division of Drug Metabolism, Faculty of Pharmaceuti-cal Sciences, Hokkaido University
-
OHASHI Kazuhiko
Laboratory of Infectious Diseases, Granduate School of Veterinary Medicine, Hokkaido University
-
YAMAMOTO Yukio
Laboratory of Toxicology Graduate School of Veterinary Medicine, Hokkaido University
-
KAMATAKI Tetsuya
Division of Drug Metabolism, Faculty of Pharmaceuti-cal Sciences, Hokkaido University
-
Masuda M
Laboratory Of Toxicology Graduate School Of Veterinary Medicine Hokkaido University
-
Tasaki Takafumi
Laboratory Of Toxicology Graduate School Of Veterinary Medicine Hokkaido University
-
Tasaki Takafumi
Laboratory Of Toxicology Department Of Environmental Veterinary Sciences Graduate School Of Veterina
-
Iwata Hisato
Laboratory Of Toxicology Department Of Environmental Veterinary Sciences Graduate School Of Veterina
-
Masuda Makihiko
Laboratory Of Toxicology Graduate School Of Veterinary Medicine Hokkaido University
-
Kamataki Tetsuya
Division Of Analytical Biochemistry Faculty Of Pharmaceutical Sciences Hokkaido University
-
Fujita Shoichi
Laboratory Of Toxicology
-
Fujita Shoichi
Laboratory Of Toxicology Graduate School Of Veterinary Medicine Hokkaido University
-
Ohashi Kazuhiko
Laboratory Of Infectious Disease Graduate School Of Veterinary Medicine Hokkaido University
-
Itoh Susumu
Division Of Cellular Physiology Faculty Of Pharmaceutical Sciences Osaka University
-
Kamataki Tetsuya
Division Of Drug Metabolism Faculty Of Pharmaceuti-cal Sciences Hokkaido University
-
Kazusaka Akio
Lavoratory Of Toxicology Graduate School Of Veterinary Medicine Hokkaido University
-
Itoh Susumu
Division Of Drug Metabolism Faculty Of Pharmaceuti-cal Sciences Hokkaido University
-
Yamamoto Yukio
Laboratory Of Horticultural Science Faculty Of Agriculture Nagoya University
-
Ohashi Kazuhiko
Laboratory Of Infectious Diseases Granduate School Of Veterinary Medicine Hokkaido University
-
Yamamoto Yukio
Laboratory Of Toxicology Graduate School Of Veterinary Medicine Hokkaido University
-
Kazusaka Akio
Graduate School Of Vet. Med. Hokkaido Univ.
関連論文
- Diazepam Metabolism in Kidney of Male and Female Rats of Varying Strain
- Expression and Sequence of CYP1A1 in Camel
- 22B-10-5 Norsalsolinol, an endogeneous dopaminergic neurotoxin, inhibits dopamine secretion in PC12 cells.
- 21WA-04-3 Seal Liver P450, as a Marker Enzyme for Marine Pollution.
- Effects of concurrent exposure to 3-methylcholanthrene and vitamin A on fetal development in rats
- Laboratory of Toxicology
- Regio- and Stereoselectivity in Propranolol Metabolism by Dog Liver Microsomes and the Expressed Dog CYP2D15^1
- Protection by Nigella sativa against carbon tetrachloride-induced downregulation of hepatic cytochrome P450 isozymes in rats
- Pesticide resistance in wild mammals : Mechanisms of anticoagulant resistance in wild rodents
- Effect of lycopene and beta-carotene on peroxynitrite-mediated cellular modifications.
- Induction of cytochrome P450-1A by the equine estrogen equilenin, a new endogenous aryl hydrocarbon receptor ligand
- Effect of components of green tea extracts, caffeine and catechins on hepatic drug metabolizing enzyme activities and mutagenic transformation of carcinogens
- Lycopene and beta-carotene ameliorate catechol estrogen-mediated DNA damage
- Antigenotoxic effect of Pleurotus cornucopiae extracts on the mutagenesis of Salmonella typhimurium TA 98 elicited by benzo[a]pyrene and oxidative DNA lesions in V 79 hamster lung cells
- P7-30 Differences of warfarin hydroxylation and vitamin K epoxide reduction between warfarin resistant and sensitive rats(Rattus rattus)(IMMUNE AND ALLERGIC SYSTEM/KIDNEYS AND URINARY EXCRETION SYSTEM/CYTOTOXICITY/OTHERS-1)(GENERAL SESSION BY POSTER PRESE
- Iodine intake as a possible cause of discontinuous decline in sperm counts : A re-evaluation of historical and geographic variation in semen quality
- The effects of antibacterial agent furazolidone and its metabolites on the liver drug metabolizing enzyme system in chicken and rat. (DRUG METABOLISM) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- O12-03 Intracellular dynamics of an endogenous dopaminergic neurotoxin, norsalsolinol, in PC12 cells
- Environmental monitoring by Cytochrome P450:Alterations of monooxygenase activities in Eriocheir japonicus in response to water pollution.
- MACROMOLECULAR BINDING OF CARCINOGENIC/MUTAGENIC N- HYDROXYARYLAMINES THROUGH O-ACETYLATION PATHWAY
- MECHANISM OF MUTATION AND METABOLIC ACTIVATION OF NITRO-, NITROSO-, HYDROXYLAMINO-COMPOUNDS IN NITRO-COMPOUNDS RESISTANT MUTANTS OF AMES TESTAR STRAIN (TA98NR, TA98/1,8-DNP_6)
- ジミリストイルホスファチジルコリンで安定化されたヘキサデカンエマルションの熱的性質
- O-18 Role of Human N-Acetyltransferase in the Metabolic Activation of 2-Phenylbenzotriazole (PBTA) Derivatives.(Proceedings of the 27th Annual Meeting)
- 21C-01-1 Metabolic Activation of PBTA-1 and PBTA-2 by Human Cytochrome P450 1A1.
- ROLE OF GROWTH HORMONE ON THE EXPRESSION OF SEX-SPECIFIC FORMS OF CYTOCHROME P-450,P-450-MALE AND P-450-FEMALE
- STUDIES ON SEX-SPECIFIC FORMS OF CYTOCHROME P-450 IN MALE AND FEMALE RATS
- Application of FT-IR and ESR spectroscopic techniques to the study of CCl_4-induced peroxidation in rat liver microsomes
- Accumulation of diacylglycerol induced by CCl_4-derived radicals in rat liver membrane and its inhibition with radical trapping reagent : FT-IR spectroscopic and HPLC chromatographic observations
- 22D-10-3 Infrared Spectroscopic Study on The Mechanism of CCl_4 Toxicity toward Membrane Phospholipids from Rat Liver.
- Inhibition of Uroporphyrinogen Oxidation-Effect of Iron- (DRUG METABOLISM) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Morphological Features and Blood Parameters of Weddell Seal (Leptonychotes weddellii) Mothers and Pups during the Breeding Season(Physiology)
- Downregulation of male-specific cytochrome P450 by profenofos
- O11-05 Induction of CYP1A1 by Equine Estrogen, Equilenin
- Generation of OH Radical in the Liver from Wilson's Disease Model, LEC Rats.
- Expression and Characterization of Dog CYP2D15 Using Baculovirus Expression System^1
- PURIFICATION AND CHARACTERIZATION OF A DOG HEPATIC CYTOCHROME P-450 ISOZYME CATALYZING β-BLOCER HYDROXYLATION
- Influence of some internal and external conditions on the induction of nitrate reductase in rice seedlings
- Testicular toxicity of profenofos in matured male rats
- Nitate assimilation in rice seedlings as affected by mineral nutrition
- The effect of TAO expression on PCD-like phenomenon development and drug resistance in Trypanosoma brucei
- Expression of alternative oxidase inhibits programmed cell death-like phenomenon in bloodstream form of Trypanosoma brucei rhodesiense
- Cytochrome P450 1A Dependent Activities in Deer, Cattle, and Horses
- Analyses of Indole Acetic Acid and Abscisic Acid Contents in Nodules of Soybean Plants Bearing VA Mycorrhizas
- Tuna Muscle Peptide, PTHIKWGD, Inhibits Leukocyte-Mediated Injury and Leukocyte Adhesion to Cultured Endothelial Cells
- Increase of Cytochrome b mRNA by Bis(2-hydroxyethyl) Trisulfide in J774A.1 Cells
- Cioning, Tissue Distribution, and Functional Expression of Two Novel Rabbit Cytochrome P450 Isozymes, CYP2D23 and CYP2D24
- Effect of reactive oxygen species on fulminant hepatitis and subsequent hepatocellular carcinoma in LEC rats and the mechanism of generation of reactive oxygen species
- EVIDENCE OF PARTIAL INVOLVEMENT OF P-450 2D IN MUTAGENIC ACTIVATION OF BENZO(a)PYRENE IN LIVER S-9 FRACTION FROM UNTREATED RATS
- Alterations in Activation and Deactivation of Mutagens in Aging Rat Liver
- ALTERED XENOBIOTICS METABOLIZING CAPACITY DURING SPONTANEOUS DEVELOPMENT OF FULMINANT HEPATITIS AND SUBSEQUENT HEPATOCELLULAR CARCINOMAS IN LEC RATS OF BOTH GENDERS
- 202 CYTOCHROME P-450 BTL (CYP2D SUBFAMILY ISOZYME) METABOLICALLY ACTIVATES CIGARETTE SMOKE EXTRACT IN RAT LlVER S-9
- Characterization of dog CYP2D15 : cDNA cloning, heterologous expression using baculovirus and drug-metabolism studies
- TOXICOLOGICAL SIGNIFICANCE OF A FORM OF CYTOCHROME P-450 HIGHLY PURIFIED FROM LIVER MICROSOMES OF PCBTREATED RATS : CATALYTIC AND IMMUNOCHEMICAL EXAMINATIONS OF A HIGH SPIN FORM OF CYTOCHROME P-448
- The Role of Glutathione in the Activation and Detoxication of a Naturally Occurring Mutagen-Carcinogen, Trp-P-2 (Regular Presentations) (Proceedings of the 10 th Symposium on Environmental Pollutants and Toxicology)
- MECHANISMS INVOLVED IN THE COVALENT BINDING OF A TRYPTOPHAN-PYROLYSATE PROMUTAGEN, TRP-P-2,TO DNA
- Metabolic activation of amino acid-pyrolysates and its relation to mutagenicity
- STUDIES ON CYTOCHROME P-450 RESPONSIBLE FOR THE OCCURRENCE OF SEX DIFFERENCE OF DRUG METABOLISM IN THE RAT
- A SENSITIVE METHOD FOR THE DETERMINATION OF BIPHENYL HYDROXYLASE ACTIVITY AND IT'S TOXICOLOGICAL APPLICATION
- MECHANISMS OF METABOLIC ACTIVATION OF A TRYPTOPHAN PYROLYSATE, 3-AMINO-1-METHYL-5H-PYRIDO [4,3-b] INDOLE
- PURIFICATION AND PROPERTIES OF CYTOCHROME P-450 AND NADPH-CYTOCHROME C (P-450) REDUCTASE FROM MICROSOMES OF HUMAN LIVERS
- STUDIES ON THE METABOLIC ACTIVATION AND THE MECHANISM OF TOXICITY OF DRUGS V. REDUCTION OF N-HYDROXY DERIVATIVE OF AN AROMATIC AMINE, 2-ACETYLAMINOFLUORENE BY CYTOCHROME P-450 (The 6th Meeting for the Study of Toxic Effect)
- DEGRADATION OF CYTOCHROME P-450 ASSOCIATED WITH METABOLIC ACTIVATION OF CARBON TETRACHLORIDE (The 5th Meeting for the Study of Toxic Effect)
- Application of Primary Hepatocytes from p53-Knockout Mice for Studies of Expression of Cyp3a
- Expression of human CYP1A2 capable of activating heterocyclic amine in Bm 6 cells using baculovirus (BmNPV) system.
- METABOLIC ACTIVATION OF AFLATOXIN B_1 BY HUMAN PLACENTAL MICROSOMES
- Formation of an Antibacterial Metabolite from a New Macrolide Compound 23-O-Benzyl-5-mycaminosyl-tylonolide (TMC-101), by a Hepatic Microsomal Drug-Metabolizing Enzyme System
- 5-2) MOLECULAR TOXICOLOGY ON CYTOCHROME P-450 IN HUMAN FETAL LIVERS
- Immunochemical Studies for the Presence of P-450 HFLa, a Form of Cytochrome P-450 in Human Fetal Livers in Human Hepatocellular Carcinoma Cells
- SPECIES DIFFERENCE OF CYTOCHROME (S) P-450 CROSS-REACTIVE WITH ANTI-P-450-MALE ANTIBODIES
- Large-scale Production of Genetically Engineered CYP3A4 in E. coli: Application of a Jarfermenter
- 21C-04-1 Inhibition of the Activity of Human Cytochrome P450 Involved in the Metabolic Activation of Procarcinogens by Green Tea Catechins.
- "S2-3 STRATEGIC PROPOSALS TO AVOID TOXIC DRUG INTERACTIONS DURING NEW DRUG DEVELOPMENT : MOLECULAR TOXICOLOGY PROPOSALS (Strategy how we can learn drug-drug interaction during the development of a new drug)
- Stable expression of CYP3A4 and CYP3A7, adult and fetal-specific forms of cytochrome P450 in human liver, in CHL cells and its application to toxicological testing.
- Effects of NO-1886 (Ibrolipim), a Lipoprotein Lipase-Promoting Agent, on Gene Induction of Cytochrome P450s, Carboxylesterases, and Sulfotransferases in Primary Cultures of Human Hepatocytes
- 221 INTRODUCTION OF CYTOCHROME P-450 cDNAS INTO CULTURED MAMMALIAN CELLS AND THEIR APPLICATION TO IN VITRO TOXICOLOGICAL STUDIES
- Cloning and characterization of cDNA encoding a prohibitin-like protein from Theileria orientalis
- IMMUNOMODULATIVE EFFECTS OF BOVINE IMMUNODEFICIENCY-LIKE VIRUS (BIV)-INFECTION AND MIXED INFECTION OF BIV AND BOVINE LEUKEMIA VIRUS ON SHEEP
- Preventive Effects of Hange-shashin-to on Irinotecan Hydrochloride-Caused Diarrhea and Its Relevance to the Colonic Prostaglandin E_2 and Water Absorption in the Rat
- Molecular Cloning of Novel Cytochrome P450 1A Genes from Nine Japanese Amphibian Species
- Protective Effects of Kampo Medicines and Baicalin against Intestinal Toxicity of a New Anticancer Camptothecin Derivative, Irinotecan Hydrochloride (CPT-11), in Rats
- The CYP1D subfamily of genes in mammals and other vertebrates.
- Metabolism of Selegiline Hydrochloride, a Selective Monoamine B-type Inhibitor, in Human Liver Microsomes
- Passive immunization with monoclonal antibodies : effects on Haemaphysalis longicornis tick infestation of BALB/c mice
- Evidence for bovine immunodeficiency virus infection in cattle in Zambia
- Evidence of bovine immunodeficiency virus in cattle in Turkey
- Seroprevalence and molecular evidence for the presence of bovine immunodeficiency virus in Brazilian cattle
- OCCURRENCE OF AUTOANTIBODY TO PROTEIN DISULFIDE ISOMERASE IN PATIENTS WITH HEPATIC DISORDER
- OCCURRENCE OF AUTOANTIBODY TO PROTEIN DISULFIDE ISOMERASE IN RATS WITH XENOBIOTIC-INDUCED HEPATITIS
- Relevance of Irinotecan Hydrochloride-Induced Diarrhea to the Level of Prostaglandin E_2 and Water Absorption of Large Intestine in Rats
- MOLECULAR CLONING OF MOUSE LIVER FLAVIN CONTAINING MONOOXYGENASE (FMO1) cDNA AND CHARACTERIZATION OF THE EXPRESSION PRODUCT : METABOLISM OF THE NEUROTOXIN, 1,2,3,4- TETRAHYDROISOQUINOLINE (TIQ)
- Kinetics of the Unrolling of the Second Leaves Detached from Rice Seedlings by Blue Light
- HIGH SUSCEPTIBILITY TO AFLATOXIN B_1 AND BENZO[A]PYRENE OF BALB3T3 A31-1-1 CELLS EXPRESSING MONKEY CYP1A1
- LOW ACTIVITY OF ALDEHYDE DEHYDROGENASE (ALDH) IN LIVER OF SUNCUS MURlNUS : POSSIBLE EXPLANATION FOR HIGH SENSITIVITY TO ALCOHOL
- Effect of High Temperature on the Development of Cyanide-Sensitive Respiration in the Germination Process of Spinach Seeds
- Inhibition of UDP-glucuronosyltransferase by Aglycons of Natural Glucuronides in Kampo Medicines Using SN-38 as a Substrate
- Use of Longitudinally Bisected Pistils of Lilium longiflorum for Studies on Self-Incompatibility
- Metabolic Alkalosis due to Feeding Chicks in Breeding Adélie Penguins Pygoscelis adeliae under Natural Conditions
- The genetic mechanisms of warfarin resistance in Rattus rattus found in the wild in Japan
- Repeated Treatment with Furazolidone Induces Multiple Cytochrome P450-Related Activities in Chicken Liver, but not in Rat Liver
- Interspecies homology of cytochrome P-450: Inhibition by anti-P-450-Male antibodies of testosterone hydroxylases in liver microsomes from various animal species including man.