Follow up Study of Patients with Peripheral Labyrinthine Lesions

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Follow up studies were performed with use of the damped pendular rotation test (0.22Hz, Max angular velocity 100°/sec) and statokinesigraphy in 7 patients with Ménière's disease as a unilateral partial labyrinthine function loss, 4 patients with unilateral total labyrinthine function loss and 4 patients with bilateral total labyrinthine function loss.1) Patients with Ménière's disease showed significant alterations of VOR-DP depending on their sensation of vertigo; this alteration was closely correlated with changes of the Romberg ratio of statokinesigraphy.2) Patients with unilateral total labyrinthine function loss showed minimum changes of VOR-DP, and the high VOR-DP persisted even though the sensation of vertigo disappeared. The Romberg ratio of area, changed significantly along with changes in the sensation of vertigo.3) Patients with bilateral total labyrinthine function loss showed higher OVR-gain (gain of Opto-Vestibular Reflex) than did those with Ménière's disease or unilateral total labyrinthine function loss. However, if the sensation of vertigo declined, patients with bilateral total labyrinthine function loss showed reduction of the high OVR-gain observed initially.
耳鼻咽喉科臨床学会の論文