Reassessment of Second Look Operation for Epithelial Ovarian Cancer.
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概要
- 論文の詳細を見る
We retrospectively reviewed 91 patients with epithelial ovarian cancer who underwent second-look operation (SLO). SLO identified a persistent tumor in 18 (19.8%) of 91 patients. Of these 18 patients, 13 (72.2%) showed disease progression after SLO. Patients with a positive SLO in which the identification of the persistent disease was only possible by washing cytological study showed better prognosis than patients with macroscopic lesions. Of the 73 patients with a negative SLO, 12 (16.4%) developed recurrence after cessation of treatment. These 12 patients were. from stage 1c to 3 with Grade 2 and 3 tumors. The SLO findings were more sensitive than the serum tumor marker in identifying persistent disease. Also we reviewed 55 patients having no SLO. Among 57 cases in stage 1 and 2 with Grade 1 tumor, there were no cases of recurrence, regardless of whether they had SLO or not. Our results suggest that SLO findings correlate well with the patient's prognosis. SLO may not be needed for patients in stage 1 and 2 with Grade 1 tumor. Patients with advanced stage disease with Grade 2 and 3 tumors have high-risk for recurrence after negative SLO. While SLO is still of benefit in management of ovarian cancer, refinements are needed to determine its indication and scheduling.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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NISHIMURA Haruo
Departmelet of Gynecology and Obstetrics, Kurume University, Faculty of Medicine
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Ushijima Kimio
Department Of Obstetrics And Gynecology Faculty Of Medicine Kurume University
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Yakushiji Michiaki
Department Of Obstetrics And Gynecology Faculty Of Medicine Kurume University
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Nishida Takashi
Department Of Biochemistry And Molecular Dentistry Okayama University Graduate School Of Medicine An
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Sugiyama Toru
Department Of Chemical Engineering Kyoto University
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MIYOSHI TADASHI
Department of Obstetrics and Gynecology, Kurume University School of Medicine
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OHKURA NAOFUMI
Department of Obstetrics and Gynecology, Kurume University School of Medicine
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