THERAPEUTIC EFFICACY OF CYTOTOXIC COMBINATION CHEMOTHERAPY IN OVARIAN "MATURE" TERATOMA
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概要
- 論文の詳細を見る
偶然にではあるが,結果的に卵巣の成熟奇形腫に対して化学療法を試みた.右側卵巣に発生した末熟奇形腫(Grade 2, FIGO Stage I-a)の術後療法として,胚細胞系腫に対する薬剤としては評価の定まっているVAC療法を施した.10コース終了した時点で,患者の下腹部に再び腫瘤形成を認めた為,再発を疑いsecond look operationを施行した.腫瘤は対側卵巣より発生した超鶏卵大の完全な成熟奇形腫であり,初回手術時には大きさ,形状ともに完全に正常であったことを考えるとVAC療法はこの成熟奇形腫の発育には何ら影響を与えなかったと思われた.正確な薬剤低抗因子の組織学的な評価は不明であるが,一般に成熟した悪性腫瘍組織は低感受性と判断されることが多い.われわれの今回の経験はこの通念を裏づけるものであり,悪性奇形腫を治療する場合,その多彩な構成成分とそれらの組織学的成熟度のばらつきを考える時,悪性度の判定として未熟成分だけでなく,制癌剤抵抗因子としての成熟成分の再評価も必要と考えられた.
- 社団法人日本産科婦人科学会の論文
- 1983-09-01
著者
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Sugiyama Toru
Department of Obstetrics and Gynecology, Iwate Medical University
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Yakushiji Michiaki
Department of Obstetrics and Gynecology, Kurume University School of Medicine
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Nishida Takashi
Department of Biochemistry and Molecular Dentistry, Okayama University Graduate School of Medicine a
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Yakushiji M
Kurume Univ. Fukuoka Jpn
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Yakushiji Michiaki
久留米大学 産婦人科
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Yakushiji Michiaki
久留米大学 第1病理
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Nishida T
Department Of Obstetrics Nad Gynecology Kurume University School Of Medicine
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ODA Takaaki
Department of Obstetrics and Gynecology, School of Medicine, Kurume University
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TAZAKI Tamikazu
Department of Obstetrics and Gynecology, School of Medicine, Kurume University
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Yakushiji Michiaki
Department Of Obstetrics And Gynecology Faculty Of Medicine Kurume University
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Nishida Takashi
Department Of Biochemistry And Molecular Dentistry Okayama University Graduate School Of Medicine An
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Sugiyama Toru
Department Of Obstetrics And Gynecology Kurume University School Of Medicine
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Oda Takaaki
Department Of Obstetrics And Gynecology School Of Medicine Kurume University
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Sugiyama Toru
Department Of Chemistry Faculty Of Science And Technology Sophia University
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Sugiyama Toru
Department Of Chemical Engineering Kyoto University
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Tazaki Tamikazu
Department Of Obstetrics And Gynecology School Of Medicine Kurume University
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Tazaki Tamikazu
Department Of Obstetrics And Gynecology Kurume University School Of Medicine
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YAKUSHIJI MICHIAKI
Department of Obstetrics and Gynecogy, Kurume University School of Medicine
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