CHEMOTHERAPY OF MALIGNANT OVARIAN TUMORS; THERAPEUTIC RESULTS OF IFOSFAMIDE
スポンサーリンク
概要
- 論文の詳細を見る
Here are reported the therapeutic results of ifosfamide on primary ovarian malignancies in 30 cases which were treated at Kurume University Hospital from September 1978 to December 1980. These cases were advanced or recurrent ones, and histologically, they consisted of serous cystadenocarcinoma in 22 cases, mucinous cystadenocarcinoma in 2 , unclassified adenocarcinoma in 1 , and malignant teratoma in 5. In the ifosfamide therapy, 2 grams or 40 mg/kg per day were given intravenously for 5 consecutive days, and as observing the blood state and the general codition, it was repeated every 3 weeks. The drug was given from 1 to 7 courses, and the average was 3.3 courses . The effect was evaluated by Koyama-Saito's criteria and Karnofsky's criteria; the response rate was 48% in the adenocarcinoma group and 20% in the malignant teratoma by the former criteria, while the , rate was 64% and 20%, respectively, by the latter one. As main side effects, there were seen hemorrhagic cystitis, nausea and vomiting, and the myelotoxicity was low.
- 社団法人日本産科婦人科学会の論文
- 1981-07-01
著者
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Yakushiji Michiaki
Department of Obstetrics and Gynecology, Kurume University School of Medicine
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Nishida Takashi
Department of Biochemistry and Molecular Dentistry, Okayama University Graduate School of Medicine a
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Yakushiji M
Kurume Univ. Fukuoka Jpn
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Inoue Tetsuro
Department of Respiratory Medicine, Tenri Hospital
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Inoue Tetsuro
Department Of Obstetrics And Gynecology Kurume University School Of Medicine
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Nishida T
Department Of Obstetrics Nad Gynecology Kurume University School Of Medicine
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KATO Toshi
Department of Obstetrics and Gynecology. School of Medicine, Kurume University
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NISHIMURA Haruo
Departmelet of Gynecology and Obstetrics, Kurume University, Faculty of Medicine
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TSUNAWAKI Akitsu
Department of Obstetrics and Gynecology Kurume University school of Medicihe, Kurume
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Yakushiji Michiaki
Department Of Obstetrics And Gynecology Faculty Of Medicine Kurume University
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Kamura Toshihatu
Department Of Obstetrics And Gynecology Kurume University School Of Medicine
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Natsuaki Yoichi
Department Of Obstetrics And Gynecology Kurume University School Of Medicine
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Nishida Takashi
Department Of Biochemistry And Molecular Dentistry Okayama University Graduate School Of Medicine An
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Kato Toshi
Department Of Obstetrics And Gynecology. School Of Medicine Kurume University
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Kato Toshi
Department Of Obstetrics And Gynecology Kurume University School Of Medicine
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Nishimura Haruo
Department Of Obstetrics And Gynecology Kurume University School Of Medicine
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Tsunawaki Akitsu
Department Of Obstetrics And Gynecology Kurume University School Of Medicihe Kurume
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Tsunawaki Akitsu
Department Of Obstetrice And Gynecology Kurume University School Of Medicine
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KATO TOSHI
Department of Obstetrics and Gynecogy, Kurume University School of Medicine
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YAKUSHIJI MICHIAKI
Department of Obstetrics and Gynecogy, Kurume University School of Medicine
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