INTRASPLENIC GRAFTING OF 7,12-DIMETHYLBENZ (A) ANTHRACENCE-TREATED OVARIAN PIECE
スポンサーリンク
概要
- 論文の詳細を見る
Immediately after a direct application of a chemical carcinogen, 7,12-dimethylbenz (a) anthracene (DMBA), the ovarian piece containing DMBA was implanted into the spleen of Wistar strain rats with or without gonadectomy. Six months after these treatments, an intrasplenic neoplasm was found in four of nine gonadectomized rats and in two of ten rats without castration. The volume of the induced tumor in the former group was 1.85cm^3 in average and that in the latter was 0.25cm^3. Histologic examination indicated that all of the induced tumors were not in the sex cord-stromal category, but adenocacinomas. No morphological differences between the tumors in the castrated group and those in the noncastrated group could be detected by light microscopy. From the difference in the volume and the incidence of the induced tumors in the two groups, it appears that the hyperstimulation of the pituitary gonadotropins in the castrated rats promoted the tumorigenic process of the induced 'epithelial' ovarian cancer caused by the DMBA application to the grafted ovarian pieces.
- 社団法人日本産科婦人科学会の論文
- 1985-01-01
著者
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Sugiyama Toru
Department of Obstetrics and Gynecology, Iwate Medical University
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Yakushiji Michiaki
Department of Obstetrics and Gynecology, Kurume University School of Medicine
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Nishida Takashi
Department of Biochemistry and Molecular Dentistry, Okayama University Graduate School of Medicine a
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Yakushiji M
Kurume Univ. Fukuoka Jpn
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Yakushiji Michiaki
久留米大学 産婦人科
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Yakushiji Michiaki
久留米大学 第1病理
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Nishida T
Department Of Obstetrics Nad Gynecology Kurume University School Of Medicine
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KATABUCHI Hideki
Department of Obstetrics and Gynecology. School of Medicine, Kurume University
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KATO Toshi
Department of Obstetrics and Gynecology. School of Medicine, Kurume University
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ARAKI Terunobu
Department of Obstetrics and Gynecology, School of Medicine, Kurume University
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NAKANAMI Masamichi
Department of Obstetrics and Gynecology, School of Medicine, Kurume University
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ODA Takaaki
Department of Obstetrics and Gynecology, School of Medicine, Kurume University
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Yakushiji Michiaki
Department Of Obstetrics And Gynecology Faculty Of Medicine Kurume University
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Kamura Toshihatu
Department Of Obstetrics And Gynecology Kurume University School Of Medicine
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Nishida Takashi
Department Of Biochemistry And Molecular Dentistry Okayama University Graduate School Of Medicine An
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Sugiyama Toru
Department Of Obstetrics And Gynecology Kurume University School Of Medicine
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Kato Toshi
Department Of Obstetrics And Gynecology. School Of Medicine Kurume University
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Kato Toshi
Department Of Obstetrics And Gynecology Kurume University School Of Medicine
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Oda Takaaki
Department Of Obstetrics And Gynecology School Of Medicine Kurume University
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Sugiyama Toru
Department Of Chemistry Faculty Of Science And Technology Sophia University
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Araki Terunobu
Department Of Obstetrics And Gynecology School Of Medicine Kurume University
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Kawagoe H
Kurume Univ. School Of Medicine Kurume Jpn
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Nakanami Masamichi
Department Of Obstetrics And Gynecology Faculty Of Medicine Kurume University
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Sugiyama Toru
Department Of Chemical Engineering Kyoto University
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KATABUCHI Hideki
Department of Obstetrics and Gynecology, Faculty of Medicine, Kurume University
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KATO TOSHI
Department of Obstetrics and Gynecogy, Kurume University School of Medicine
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YAKUSHIJI MICHIAKI
Department of Obstetrics and Gynecogy, Kurume University School of Medicine
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