STUDIES ON THE VASCULAR ACTION OF BRADYKININ
スポンサーリンク
概要
- 論文の詳細を見る
Bradykinin (BK) is widely regarded as a potent vasodilator capable of increasing blood flow, increasing vascular permeability, and lowering systemic blood pressure through microcirculatory dilatation.<BR> On the other hand, reports have appeared in the literature which indicate that BK may constrict some vessels. Lecomte and Trouquet (1), Gersmyer and Spitzbarth (2) and Klupp and Konzett (3) demonstrated the constriction of the lung vessel. Guth et al. (4) and Rowley (5) reported that BK caused venoconstriction of the rabbit ear and rat skin, respectively. Shimamoto et al. (6) also reported the constriction of the rabbit saphenous vein by BK.<BR> The present experiments were undertaken to clarify the BK action on the various portions of blood vessel using several methods. Furthermore some tests were tried to study on the mechanism of venoconstrictive action of BK.
- 社団法人 日本薬理学会の論文
著者
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Nakashima Mitsuyoshi
Deparrment Of Pharmacology Hamamatsu University School Of Medicine
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Maeda Kiyoshi
Department Of Psychiatry And Neurology Kobe Graduate School Of Medicine
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Sekiya Atsushi
Dept. Of Pharmacol. Fujita-gakuen Univ. School Of Med.
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Sekiya Atsushi
Department Of Public Health/health Information Dynamics Field Of Social Life Science Nagoya Universi
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Yamamoto Junnosuke
Department Of Internal Medicine Kakegawa City General Hospital
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Oya Hiroshi
Department Of Astronomy And Geophysics Tohoku University
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HIRAKO Ikuo
Department of Pharmacology, Nagoya University School of Medicine
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Sekiya Atsushi
Department Of Chemistry And Biochemistry School Of Advanced Science And Engineering Waseda University
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MAEDA Kiyoshi
Department of Pharmacology, Nagoya University School of Medicine
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OYA Hiroshi
Department of Pharmacology, Nagoya University School of Medicine
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YAMAMOTO Junnosuke
Department of Pharmacology, Nagoya University School of Medicine
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Maeda Kiyoshi
Department of Medical Rehabilitation, Kobe Gakuin University
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