CARDIOVASCULAR ACTION OF PROPRANOLOL IN RATS UNDER VARIOUS ANESTHETIC PROCEDURES
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概要
- 論文の詳細を見る
We previously reported that the pressor action of propranolol was observed in the rat anesthetized with urethane. In the present study, rats, anesthetized with pentobarbitone or ether, treated with curare or unanesthetized, were used to investigate the influence of anesthetics on the blood pressure response to propranolol. Propranolol always produced a pressor response under these experimental conditions as well as urethane anesthesia. But under pentobarbitone anesthesia, the magnitude of the pressor action was significantly lower than that obtained under the other experimental conditions. It is concluded that the choice of urethane as the anesthetic does not create a situation irrelevant to that found with other anesthetics and that the cardiovascular responses of rat to propranolol are unique when compared to other species.
- 社団法人 日本薬理学会の論文
著者
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Sekiya Atsushi
Dept. Of Pharmacol. Fujita-gakuen Univ. School Of Med.
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Sekiya Atsushi
Department Of Public Health/health Information Dynamics Field Of Social Life Science Nagoya Universi
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Yamamoto Junnosuke
Department Of Internal Medicine Kakegawa City General Hospital
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Maekawa Hiroshi
Department Of Mechanical And Control Engineering University Of Electro-communications
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Sekiya Atsushi
Department Of Chemistry And Biochemistry School Of Advanced Science And Engineering Waseda University
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SEKIYA Atsushi
Department of Pharmacology, Fujita-Gakuen University, School of Medicine
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