The role of calcium ion in methoxamine-induced amylase release from parotid glands of euthyroid and hypothyroid rats.
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概要
- 論文の詳細を見る
The change in responsiveness to α-adrenergic stimulation and to calcium ions in amylase release from parotid glands of hypothyroid rats was compared with that in euthyroid rats. Calcium depletion and addition of verapamil or W-7 in the medium caused a decrease in methoxamine-induced amylase release in both eu- and hypothyroid rats. Moreover, addition of calcium ions to Ca<SUP>2+</SUP>-free medium markedly increased the methoxamine-induced amylase release in proportion to its concentration in hypothyroid rats. These results suggest that calcium ions play an important role in methoxamine-induced amylase release from parotid glands of hypothyroid rats as well as those of the euthyroid ones.
- 公益社団法人 日本薬理学会の論文
著者
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Tachibana Masakatsu
Department Of Pharmacology Fujita-gakuen Health University School Of Medicine
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Maekawa Hiroshi
Department Of Mechanical And Control Engineering University Of Electro-communications
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Nomura Takahide
Department Of Pharmacology School Of Medicine Fujita Health University
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Nomura Hiroko
Department Of Applied Chemistry Faculty Of Science And Engineering Chuo University
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HAGINO Yasumichi
Department of Biochemistry, Nagoya University School of Medicine
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IZUHARA Ken
Department of Pharmacology, Fujita-Gakuen Health University School of Medicine
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