Randomized Double-Blind Trial of Intracoronary Urokinase for Acute Myocardial Infarction : Multicenter Study : 50th Annual Scientific Session of the Japanese Circulation Society
スポンサーリンク
概要
- 論文の詳細を見る
The efficacy of intracoronary urokinase (UK) in an acute myocardial infarction has not been firmly established in a randomized fashion. Two hundred and ten patients were randomized to UK therapy (107 patients) and placebo (103 patients). Successful recanalization was achieved in 74% of the UK group vs 17% in the placebo group (p<0.01). The success rate was dose dependent up to 960,000 I.U. Clinical course was favorable and left ventricular enddiastolic pressure was reduced significantly in the UK group compared with the placebo group (p<0.05). Ejection fraction one month after the study was better in the reopened group than in the occluded group. Thus, early administration of UK can establish coronary reflow in a high proportion of patients and appears to favor the clinical course.
- 1987-09-20
著者
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NARUSE Mitsuhide
NHO Kyoto Medical Center
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KIMURA Kenjiro
St. Marianna University School of Medicine
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Nakamaru Mitsuaki
Nho Kyoto Medical Center
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Kodama Kazuhisa
Osaka Police Hospital Cardiovasucular department
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Kambara Hirofumi
The Kyoto And Shiga Myocardial Infarction (kysmi) Study Group:cardiovascular Center Osaka Red Cross
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Kambara Hirofumi
大阪赤十字病院
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KAMBARA Hirofumi
Osaka Red Cross Hospital
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Kambara Hirofumi
Kyoto University
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Kawai Chuichi
Kyoto University
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Kawai Chuichi
The Japan Multicenter Investigation For Cardiovascular Diseases-b (jmic-b) Study Group
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Nakajima Mitsuyoshi
Nho Kyoto Medical Center
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NAGASE Mitsumasa
Teikyo University School of Medicine
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KAMMATSUSE KATSUO
Nihon University Hospital, Surugadai
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Kajiwara Nagao
Nihon University School of Med
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Kawai Chuichi
The Third Division Department Of Internal Medicine Kyoto University And Department Of Medicine Beth
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Kajiwara Nagao
Nihon University
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Sasayama Shigetake
The Third Division Of Medicine Kyoto University
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Sasayama Shigetake
Hamamatsu Rosai Hospital
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Kodama Kazuhisa
Osaka Police Hospital
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Kammatsuse Katsuo
Nihon University
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Kambara Hirofumi
The 3rd Division Department Of Internal Medicine Faculty Of Medicine Kyoto University
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SATO Hikaru
Hiroshima City Hospital
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Sasayama Shigetake
Toyama Medical and Pharmaceutical Univ.
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NAKASHIMA MITSUYOSHI
Hamamatsu Institute of Clinical Pharmacology and Therapeutics
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Kawai Chuichi
The Third Division Department Of Internal Medicine Faculty Of Medicine Kyoto University
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NOBUYOSHI MASAHIKO
Kokura Memorial Hospital
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Kodama Kazuhisa
Internal Medicine Nephrology And Hypertension St. Marianna University School Of Medicine
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Nakashima Mitsuyoshi
Deparrment Of Pharmacology Hamamatsu University School Of Medicine
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Sawada Shigeo
Virus Center National Kyoto Hospital
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Kambara Hirofumi
The Third Division Department Of Internal Medicine Kyoto University
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Sasayama Shigetake
Department Of Cardiovascular Medicine Graduate School Of Medicine Kyoto University
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Sasayama Shigetake
Division Of Medicine Hamamatsu Rosai Hospital Shizuoka
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Kodama Kazuhisa
Osaka Acute Coronary Insufficiency Study (oacis) Group
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Sasayama Shigetake
Department Of Cardiology Doshisha University
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Sasayama Shigetake
The Third Division Department Of Internal Medicine Faculty Of Medicine Kyoto University
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Kamabara Hirofumi
Osaka Red Cross Hospital
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Nagase Mitsumasa
Nho Kyoto Medical Center
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Sasayama Shigetake
Third Division Department Of Internal Medicine Kyoto University
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Nakashima Mitsuyoshi
Hamamatsu Institute Of Clinical Pharmacology & Therapeutics
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Nakajima Mitsuyoshi
Deparrment Of Pharmacology Hamamatsu University School Of Medicine
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Sasayama Shigetake
Second Division Internal Medicine Toyama Medical And Pharmaceutical School
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Kambara H
Kyoto University
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Sasayama Shigetake
Thesecond Department Of Internal Medicine Toyama Medical And Pharmaceutical University
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