Protective Effects of Epigallocatechin Gallate on Paraquat-Induced Oxidative Stress in Rats
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概要
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The protective effect of epigallocatechin gallate (EGCg) on paraquat-induced oxidative stress was determined in rats. Decreases in food intake, body weight gain, and liver triacylglycerol level, which were all caused by being fed a paraquat diet, were mitigated by supplementing EGCg in the paraquat diet. Blood and liver antioxidative enzyme activities were not significantly different among the control, paraquat, and paraquat+EGCg diets-fed rats. The liver thiobarbituric acid reactive substances, however, markedly decreased when the paraquat diet was supplemented with EGCg. These results indicate that EGCg acted in a preventive fashion against paraquat-induced oxidative stress.
著者
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Igarashi Kiharu
Department Of Agricultural Chemistry Faculty Of Agriculture Yamagata University
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Araki Yumi
Department Of Bioresourse Engineering Faculty Of Agriculture Yamagata University
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Yoshiki Yumiko
Department Of Applied Biological Chemistry Faculty Of Agriculture Tohoku University
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Okubo Kazuyoshi
Department Of Applied Biological Chemistry Faculty Of Agriculture Tohoku University
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Suzuki Orie
Department Of Bioproduction Faculty Of Agriculture Yamagata University
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ARAKI Yumi
Department of Bioproduction, Faculty of Agriculture, Yamagata University
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