Synthesis of lipid derivatives of pyrrole polyamide and their biological activity
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概要
- 論文の詳細を見る
Novel fatty acyl and phospholipid derivatives of pyrrole polyamide were synthesized. Their cytotoxicity against a cancer cell line of MT-4 cells and those infected by human immunodeficiency virus (HIV) was examined. Although no anti-HIV activity was found, their cytotoxicitty against the cancer cells was significantly enhanced by introducing a lipophilic group into the pyrrole polyamide.
- Japan Society for Bioscience, Biotechnology, and Agrochemistryの論文
著者
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YAMAMOTO Masahiko
Department of Materials Science and Engineering, Graduate School of Engineering, Osaka University
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Miura Yoshie
Department of Laboratory Medicine, Yamanashi Medical University
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Izumi Minoru
Department Of Chemistry Graduate School Of Science Osaka University
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SHIMIZU Sakayu
Department of Agricultural Chemistry, Faculty of Agriculture, Kyoto University
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Nakajima Shuhei
Department Of Bioresources Chemistry Faculty Of Agriculture Okayama University
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TANAMOTO Ken-ichi
National Institute of Health Sciences
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Baba Naomichi
Department Of Bioresources Chemistry Faculty Of Agriculture Okayama University
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ZHU Changjin
School of Chemical Engineering & Environment, Beijing Institute of Technology
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YI Lui
School of Chemical Engineering & Environment, Beijing Institute of Technology
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RONG Zheng
School of Chemical Engineering & Environment, Beijing Institute of Technology
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