Synthesis of lipid derivatives of pyrrole polyamide and their biological activity
スポンサーリンク
概要
- 論文の詳細を見る
Novel fatty acyl and phospholipid derivatives of pyrrole polyamide were synthesized. Their cytotoxicity against a cancer cell line of MT-4 cells and those infected by human immunodeficiency virus (HIV) was examined. Although no anti-HIV activity was found, their cytotoxicitty against the cancer cells was significantly enhanced by introducing a lipophilic group into the pyrrole polyamide.
- Japan Society for Bioscience, Biotechnology, and Agrochemistryの論文
- 2007-04-23
著者
-
YAMAMOTO Masahiko
Department of Materials Science and Engineering, Graduate School of Engineering, Osaka University
-
Miura Yoshie
Department of Laboratory Medicine, Yamanashi Medical University
-
Murata Y
Graduate School Of Natural Science And Technology Okayama University
-
Miura Yoshie
川崎医科大学 衛生学
-
Miura Yoshie
Department Of Laboratory Medicine Yamanashi Medical University
-
Miura Yoshie
Dep. Of Biofunctional Chemistry Graduate School Of Natural Sci. And Technol. Okayama Univ.
-
Shimizu S
Agricultural Sciences Kyoto University
-
Izumi Minoru
Department Of Chemistry Graduate School Of Science Osaka University
-
Izumi Minoru
Department Of Bioresources Chemistry Faculty Of Agriculture Okayama University
-
SHIMIZU Sakayu
Department of Agricultural Chemistry, Faculty of Agriculture, Kyoto University
-
Nakajima S
Graduate School Of Natural Science And Technology Okayama University
-
Nakajima Shuhei
Department Of Bioresources Chemistry Faculty Of Agriculture Okayama University
-
TANAMOTO Ken-ichi
National Institute of Health Sciences
-
Shimizu Sakayu
Department Of Agricultural Chemistry Faculty Of Agriculture Kyoto University
-
Miura Y
Department Of Applied Biological Science Tokyo Noko University
-
Miura Yutaka
Applied Bioresearch Center Kirin Brewry Co. Ltd.
-
Miura Yutaka
Department Of Agricultural Chemistry Faculty Of Agriculture The University Of Tokyo
-
Baba N
Graduate School Of Natural Science And Technology Okayama University
-
Baba Naomichi
Department Of Bioresources Chemistry Faculty Of Agriculture Okayama University
-
Baba Naomichi
Department Of Biore Sources Chemistry Faculty Of Agriculture Okayama University
-
Izumi Minoru
Div. Of Bioscience Graduate School Of Natural Sci. And Technol. Okayama Univ.
-
Nakajima Shuhei
Div. Of Bioscience Graduate School Of Natural Sci. And Technol. Okayama Univ.
-
Nakajima Shuhei
Department Of Agricultural Science Okayama University
-
Baba Naomichi
Div. Of Bioscience Graduate School Of Natural Sci. And Technol. Okayama Univ.
-
ZHU Changjin
School of Chemical Engineering & Environment, Beijing Institute of Technology
-
YI Lui
School of Chemical Engineering & Environment, Beijing Institute of Technology
-
RONG Zheng
School of Chemical Engineering & Environment, Beijing Institute of Technology
-
Shimizu S
Iwate Univ. Iwate Jpn
-
Rong Zheng
School Of Chemical Engineering & Environment Beijing Institute Of Technology
-
Tanamoto Ken-ichi
National Institute Of Health Sciences Division Of Food Additives
-
Zhu Changjin
School Of Chemical Engineering & Environment Beijing Institute Of Technology
-
Yi Lui
School Of Chemical Engineering & Environment Beijing Institute Of Technology
-
Yamamoto Masahiko
Department Of Biofunctional Chemistry Graduate School Of Natural Science And Technology Okayama Univ
-
Miura Yoshie
Department Of Biofunctional Chemistry Graduate School Of Natural Science And Technology Okayama Univ
-
IZUMI Minoru
Department of Biofunctional Chemistry, Graduate School of Natural Science and Technology, Okayama University
-
BABA Naomichi
Department of Biofunctional Chemistry, Graduate School of Natural Science and Technology, Okayama University
関連論文
- 1Hp23 ラッカーゼの酵母細胞表層提示による新規リグニン分解・前処理系の構築(バイオマス・資源・エネルギー工学,一般講演)
- Acidolysis and Glyceride Synthesis Reactions Using Fatty Acids with Two Pseudomonas Lipases Having Different Substrate Specificities(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- 乳酸菌による共役脂肪酸生産
- 1D11-5 油糧微生物Mortierella alpina 1S-4におけるω3脂肪酸不飽和化酵素遺伝子の過剰発現による脂肪酸組成改変(発酵生理学・発酵工学,一般講演)
- 油脂をつくる微生物の探索と育種--最近の進歩 (特集:微生物バイオテクノロジー)
- 2S3-PM1 油糧微生物Mortierella alpina 1S-4がつくる有用油脂の生産性向上への展開(脂質工学:機能性油脂の創製をめざして,シンポジウム)
- 2D12-1 油糧微生物Mortierella alpina 1S-4より誘導された変異株によるtriarachidonyl glycerolの蓄積(発酵生理学・発酵工学,一般講演)
- 2Ha01 リグニンのバイオリファイナリーをめざしたラッカーゼアイソザイムの酵母細胞表層提示(バイオマス・資源・エネルギー工学,一般講演)
- Cloning, sequencing and expression analysis of a gene encoding alcohol oxidase in Paenibacillus sp. AIU 311(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Alkaline pH enhances farnesol production by Saccharomyces cerevisiae(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
- Production and characterization of alcohol oxidase from Penicillium purpurescens AIU 063(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Purification and Characterization of a New Aldehyde Oxidase from Pseudomonas sp. AIU 362(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Expression and Ca^ Dependency of Plasma Membrane K^+ Channels of Tobacco Suspension Cells Adapted to Salt Stress
- Crystal Structure and Magnetic Properties of Cr-Doped AlN Films with Various Cr Concentrations
- Evolution of Magnetic State of Ultrathin Co Films with Volmer-Weber Growth
- Formation of L1_0-type Ordered FePd Phase in Multilayers Composed of Fe and Pd
- Structural and Magnetic Properties of Dy/Cr Multilayers and Bilayers Grown by Molecular-Beam Deposition
- Magnetic Property and Morphology of Fe Film Grown on Self-Organized SrTiO_3 (001) Substrate with Inclined Angle
- Surface Structure of Self-Organized Sapphire (0001) Substrates with Various Inclined Angles
- Morphology of Fe Film Grown on Self-Organized SrTiO_3(001) Substrates with Inclined Angles
- Magnetic States and Magnetization Processes of Ni-Fe/Hf Annular Dots as Candidates of Non-Volatile Memory Cells
- Magnetic and Electric Properties in C/Mn/C/Si Multilayers
- Effects of Sphingolipids on the Fate of FRTL-5 Cells
- Molecular-Beam Epitaxial Growth and Structures of Dy on (100) and (211)Cr Thin Films
- Magnetic States and Magnetization Process in Ni-Fe Sub-micron Cup-Shaped Dots
- Studies of self-Organized Steps and Terraces in inclined SrTiO_3 (001) Substrate by Atomic Force Microscopy
- Magnetic Properties in Mn/Si-O/Si(100)-substrate Systems and Mn/Si-O/Si Trilayers
- Keynote Lecture in the 13^th Japanese Society of Immunotoxicology(JSIT 2006) : Pathophysiological Development and Immunotoxicology : what we have found from the researches related to the silica and silicate such as asbestos
- Investigation of Self-Organized Steps and Terraces in SrTiO_3 (001) Substrate Inclined in [110] Direction by Scanning Tunneling Microscopy
- Rho-Mediated Phosphorylation of Focal Adhesion Kinase and Myosin Light Chain in Human Endothelial Cells Stimulated with Sphingosine 1-Phosphate, a Bioactive Lysophospholipid Released from Activated Platelets
- Magnetization Reversal with In-Plane Magnetic Field in Asymmetric Ring Dots
- Molecular-Beam Epitaxial Growth of(001)Cr/Al/Cr/Al Quadrilayer Superlattice Containing One-Monolayer-Thick Cr Layers
- Stranski-Krastanov Growth of Al on Ag Layers during Molecular Beam Epitaxy of(111) Al/Ag Superlattices
- Molecular-Beam Epitaxial Growth of Short-Period(001)Al/Ag/Cr Superlattices with Intermediary Ag Layers
- Solid-State Amorphization in Al/Pd Multilayer during Near-Room-Temperature Molecular-Beam Deposition
- Molecular Beam Epitaxial Growth and Structures of Al/Ag Superlattices
- Structure and Magnetic Properties of [Ag/Ni/Au] and [Au/Ni/Ag] Superlattices
- Field-Ion Images of Ordered Ni_3Mo Alloy and Their Computer Simulation
- Field-Evaporation End Form of Ordered Ni_4Mo Alloy
- A Method of Determining the Types of Ordered Domains of β-Ni_4Mo in Field-Ion Images
- Field-Ion Microscope Study of Early Stages of Ordering in Ni_4Mo Alloy
- Immunological alterations found in mesothelioma patients and supporting experimental evidence
- Keynote Lecture in the 13th Japanese Society of Immunotoxicology (JSIT 2006) : Pathophysiological Development and Immunotoxicology: what we have found from research related to silica and silicate such as asbestos(Report of the 13th Annual M
- Syntheses of Sphingomyelins and Ceramides Bearing a Docosahexaenoyl of Arachidonoyl Group
- Relationship between pollen counts of Cryptomeria japonica and Cupressaceae and the severity of allergic symptoms
- The Inhibitory Effect of Dibutyryl Cyclic AMP on Docosahexaenoic Acid-Induced Apoptosis in HL-60 Cells through Activation of the Phosphatidylinositol-3 Kinase Pathway
- Effects of Exogenous Application of Proline and Betaine on the Growth of Tobacco Cultured Cells under Saline Conditions(Plant Nutrition)
- Docosahexaenoic Acid Induces Apoptosis via the Bax-Independent Pathway in HL-60 Cells
- Simple Determination of Trace Amounts of Anionic Surfactants in River Water by Spectrophotometry Combined with Solid-phase Extraction
- Degradation of Ethyl Docosahexaenoate by γ-Ray Irradiation and Suppression of This Degradation by Antioxidants
- Inhibitory Effects of Esculetin on Melanin Biosynthesis (Pharmacology)
- Reduction in Photostability by the Esterification of β-Cryptoxanthin
- Mushroom Tyrosinase Inhibitory Activity of Esculetin Isolated from Seeds of Euphorbia lathyris L.(Organic Chemistry)
- Negative Correlation between the Ratio of K^+ to Na^+ and Proline Accumulation in Tobacco Suspension Cells
- Alterations in Ca^-Binding on Plasma Membrane after Adaptation to Salt Stress of Tobacco Cells in Suspension
- Exogenous Proline Mitigates the Inhibition of Growth of Nicotiana tabacum Cultured Cells under Saline Conditions
- Analysis of fatty acids and sterols of plasma membrane and tonoplast isolated from salt-stress adaptation of Tobacco cultured cells in suspension
- Inward rectifying K^+ channel in the plasma membrane and salt adaptation of tobacco cultured cells in suspension
- Ca^ Regulation of Outward Rectifying K^+ Channel in the Plasma Membrane of Tobacco Cultured Cells in Suspension : a Role of the K^+ Channel in Mitigation of Salt-Stress Effects by External Ca^
- EFFECTS OF SALINITY ON CA^-BINDING TO THE PLASMA MEMBRANE OF TOBACCO SUSPENSION CELLS AND BARLEY MESOPHYLL CELLS WITH IMPLICATIONS TO SALT TOLERANCE
- Effect of Na^+ on Ca^-Binding on the Plasma Membrane of Barley Mesophyll Cells : an Electrophoretic Study
- COMPOSITION OF FREE AMINO ACIDS IN SALT-UNADAPTED AND -ADAPTED TOBACCO CULTURED CELLS
- SALT ADAPTATION OF INWARD-RECTIFYING K^+ CHANNELS IN PLASMA MEMBRANE OF TOBACCO CULTURED CELLS
- Inheritance of Crystal Structure in Cu/Co and Co/Cu Bilayers Grown on MgO(100) Substrate
- Scanning Tunneling Microscopy and Atomic Force Microscopy Study on Interface between Molecular-Beam-Grown Pt Film and Si (111) Substrate
- Scanning Tunneling Microscope and Atomic Force Microscope Observation of Topography of Molecular-Bearm-Epitaxy-Grown Pt Films on Cu Buffer Layer and Si(111)-(7×7) Substrate
- Sensory Conduction Study of Cisplatin Neuropathy: Preservation of Small Myelinated Fibers
- Spin-Crossover Behaviors of Iron(III) Compounds with Strong Intermolecular Interactions
- Interlayer Exchange Coupling of Fe/Y Multilayers
- Change of Interlayer Exchange Coupling in Fe/Y Multilayers by Hydrogenation
- EFFECT OF FLUORIDE ON PHYSIOLOGICAL ION MOBILIZATIONS IN RATS
- Mossbauer Study on the Electron Transfer Rate Depending on the Intermolecular Interaction in Iron(II,III) Mixed-Valence Complex
- Computer-Simulated Field-Ion Images of Ni_4Mo Alloy for Statistically Homogeneous Ordering
- Synthesis of lipid derivatives of pyrrole polyamide and their biological activity
- Cytosolic Alkalization and Cytosolic Calcium Oscillation in Arabidopsis Guard Cells Response to ABA and MeJA
- Roles of AtTPC1, Vacuolar Two Pore Channel 1, in Arabidopsis Stomatal Closure
- Myrosinases, TGG1 and TGG2, Redundantly Function in ABA and MeJA Signaling in Arabidopsis Guard Cells
- Roles of RCN1, Regulatory A Subunit of Protein Phosphatase 2A, in Methyl Jasmonate Signaling and Signal Crosstalk between Methyl Jasmonate and Abscisic Acid
- Closing Plant Stomata Requires a Homolog of an Aluminum-Activated Malate Transporter
- Effects of the Fermentation Product of Herbs by Lactic Acid Bacteria against Phytopathogenic Filamentous Fungi and on the Growth of Host Plants(MISCELLANEOUS)
- Antifungal Activity of the Fermentation Product of Herbs by Lactic Acid Bacteria against Tinea(MISCELLANEOUS)
- Chitosan-Induced Stomatal Closure Accompanied by Peroxidase-Mediated Reactive Oxygen Species Production in Arabidopsis
- Quantitative Analysis of the Effects of Diffusates from Plant Roots on the Hatching of Meloidogyne chitwoodi from Young and Senescing Host Plants
- The Effects of Methylglyoxal on Glutathione S-Transferase from Nicotiana tabacum
- Proline and Glycinebetaine Ameliorated NaCl Stress via Scavenging of Hydrogen Peroxide and Methylglyoxal but Not Superoxide or Nitric Oxide in Tobacco Cultured Cells
- Artificial Food Colorants Inhibit Superoxide Production in Differentiated HL-60 Cells
- Proline and Glycinebetaine Confer Cadmium Tolerance on Tobacco Bright Yellow-2 Cells by Increasing Ascorbate-Glutathione Cycle Enzyme Activities
- Exogenous Proline and Glycinebetaine Suppress Apoplastic Flow to Reduce Na^+ Uptake in Rice Seedlings
- Induction of Apoptosis by β-Carotene and Dimethyl Tetrasulfide Assisted by UVA Irradiation in HL-60 Cells
- (-)-Epigallocatechin-3-gallate Potentiates the Cytotoxicity Induced by Benzyl Isothiocyanate and Hydrogen Peroxide in Human Jurkat T Lymphocytes
- Effect of Dimethyl Sulfides on the Induction of Apoptosis in Human Leukemia Jurkat Cells and HL-60 Cells
- Deficient Glutathione in Guard Cells Facilitates Abscisic Acid-Induced Stomatal Closure but Does Not Affect Light-Induced Stomatal Opening
- Structure-Dependent Photodegradation of Carotenoids Accelerated by Dimethyl Tetrasulfide under UVA Irradiation
- Synthesis of lipid derivatives of pyrrole polyamide and their biological activity
- The Involvement of Intracellular Glutathione in Methyl Jasmonate Signaling in Arabidopsis Guard Cells
- Yeast Elicitor-Induced Stomatal Closure and Peroxidase-Mediated ROS Production in Arabidopsis
- The Roles of CATALASE2 in Abscisic Acid Signaling in Arabidopsis Guard Cells
- Inhibitory Effects of Methylglyoxal on Light-Induced Stomatal Opening and Inward K^+ Channel Activity in Arabidopsis
- Mechanisms of the Selenium Tolerance of the Arabidopsis thaliana Knockout Mutant of Sulfate Transporter SULTR1;2
- Isolation and Characterization of Pepsin-Soluble Collagen from Abalone (Haliotis discus hannai) Gastropod Muscle Part II