(-)-Epigallocatechin-3-gallate Potentiates the Cytotoxicity Induced by Benzyl Isothiocyanate and Hydrogen Peroxide in Human Jurkat T Lymphocytes

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概要

• 論文の詳細を見る

• (−)-Epigallocatechin-3-gallate (EGCG)-induced apoptosis was along both the extracellular signal-regulated protein kinase (ERK) and c-jun N-terminal kinase (JNK) pathways in Jurkat cells. Co-treatment with EGCG potentiated the cytotoxicity induced by benzyl isothiocyanate (BITC) and H2O2, both being inhibited by ERK and JNK inhibitors. These results suggest the significant role of mitogen-activated protein kinase (MAPK) signaling in the apoptosis induction regulated by EGCG alone and in combination.

• 社団法人 日本農芸化学会の論文
• 2008-11-23

著者

• NAKAMURA Yoshimasa

  Graduate School of Natural Science and Technology, Okayama University

• SHIMOISHI Yasuaki

  Graduate School of Natural Science and Technology, Okayama University

• MURATA Yoshiyuki

  Graduate School of Natural Science and Technology, Okayama University

• Murata Y

  Graduate School Of Natural Science And Technology Okayama University

• Miura Yoshie

  川崎医科大学 衛生学

• Miura Yoshie

  Dep. Of Biofunctional Chemistry Graduate School Of Natural Sci. And Technol. Okayama Univ.

• Shimoishi Yasuaki

  Div. Of Bioscience Graduate School Of Natural Sci. And Technol. Okayama Univ.

• Nakamura Yoshimasa

  Div. Of Bioscience Graduate School Of Natural Sci. And Technol. Okayama Univ.

• Nakamura Yoshimasa

  Graduate School Of Agriculture Kyoto University

• Masamoto Yukimitsu

  Graduate School Of Natural Science And Technology Okayama University

• Murata Yoshiyuki

  Graduate School Of Natural Science And Technology Okayama University

• ZHU Beiwei

  College of Bio & Food Technology, Dalian Polytechnic University

• Zhu Beiwei

  Department Of Biotechnology School Of Biological And Food Engineering Dalian Polytechnic University

• WU Haitao

  Graduate School of Natural Science and Technology, Okayama University

• YOKOYAMA Tomoko

  Graduate School of Natural Science and Technology, Okayama University

• Murata Yoshiyuki

  Graduate School Of Natural Science And Technology Okayama Univ.

• Yokoyama Tomoko

  Graduate School Of Natural Science And Technology Okayama University

• Wu Haitao

  Graduate School Of Natural Science And Technology Okayama University

• Murata Yoshiyuki

  Okayama Univ. Okayama Jpn

• Nakamura Yoshimasa

  Graduate School Of Natural Sci. Technol. Okayama Univ.

• Murata Yoshiyuki

  Graduate School Of Natural Sci. And Technol. Okayama Univ.

• Shimoishi Yasuaki

  Graduate School Of Natural Science And Technology Okayama University

• MURATA Yoshiyuki

  Graduate School of National Science and Technology, Okayama University

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