プーアル茶抽出物および紅茶テアフラビンのマウス糖吸収抑制作用

概要

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Effects of a water extract prepared from pu-erh tea leaves and the fractions elutedby column chromatography with Diaion HP-20, and theaflavin- 3'-gallate (TF-3'G) of black tealeaves on absorption of sugars in mice were investigated. The simultaneous oraladministration of pu-erh tea extract at a dose of 20 mg/mouse with maltose or sucroseinhibited the postprandial elevations of plasma glucose levels as same as the administration ofD-xylose with sugars. This effect showed a dose-dependency. The increases of smallintestinal maltase activity and plasma insulin level were significantly suppressed by thesimultaneous administration of pu-erh tea extract with maltose. Similar actions were observedwhen green tea extract and TF-3'G at a dose of 20 mg were administered. There was nodifference between the functions of two fractions, water eluate and methanol eluate, preparedfrom pu-erh tea extract with Diaion HP-20 column, though the total polyphenol amounts ofthem were 13.8%(w/w) and 42.5%(w/w). Therefore, it is thought that the polyphenolicingredient participates in the action partly, but the existence of other active ingredients isexpected. These results indicate that pu-erh tea and black tea could be beneficial foodmaterials for inhibiting the sugar absorption.
2012-01-31