Effects of Chinese and Paraguayan Medicinal Plants on the Duration of Immobility of Mice in the Forced Swimming Test
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概要
- 論文の詳細を見る
Extracts of 5 Chinese and 3 Paraguayan medicinal plants were examined for their effects on the duration of the forced swimming-induced immobility in mice to evaluate their antidepressant activities. In the case of MeOH extracts, Ginseng Radix was the most active followed by Rosmarinus officinalis LINN. In the case of 30% EtOH extracts, the activities were in the decreasing order, Psidium guajava LINN., Rosmarinus officinalis LINN., Valerianae Radix and Zizyphi Fructus. Hot 30% EtOH extracts of Zizyphi Fructus and Theobroma cacao L. showed potent activities. The activities of EtOAc solubles of Psidium guajava LINN, and H_2O solubles of Valerianae Radix at 100 mg/kg were comparable to that of imipramine at 20 mg/kg.
- 日本生薬学会の論文
- 1997-02-20
著者
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Yasuda Hideyuki
Lotte Central Laboratory Co. Ltd.
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Matsunaga K
Tohoku Univ. Sendai Jpn
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Ohizumi Yasushi
Department Of Pharmaceutical Molecular Biology Faculty Of Pharmaceutical Sciences Tohoku University
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Ito Masanori
Lotte Central Laboratory Co. Ltd.
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Matsunaga Kimihiro
Department Of Pharmaceutical Molecular Biology Faculty Of Pharmaceutical Sciences Tohoku University
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LU XIAO-CHUAN
Department of Pharmaceutical Molecular Biology, Faculty of Pharmaceutical Sciences, Tohoku Universit
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TAKIGUCHI TOSHIO
Lotte Central Laboratory, Co., Ltd.
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Takiguchi Toshio
Lotte Central Laboratory Co. Ltd.
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Lu Xiao-chuan
Department Of Pharmaceutical Molecular Biology Faculty Of Pharmaceutical Sciences Tohoku University
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Ohizumi Yasushi
Department Of Anti-dementia Functional Food Development Graduate School Of Engineering Tohoku Univer
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Matsunaga Kimihiro
Department of Applied Biological Sciences, Faculty of Agriculture, Saga University
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