Honeybee Royal Jelly and Nobiletin Stimulate CRE-Mediated Transcription in ERK-Independent and -Dependent Fashions, Respectively, in PC12D Cells
スポンサーリンク
概要
- 論文の詳細を見る
- 2011-08-20
著者
-
三巻 祥浩
School Of Pharmacy Tokyo Univ. Of Pharmacy And Life Sciences
-
Yamakuni Tohru
Tohoku Univ. Sendai Jpn
-
Oshima Yasukatsu
Department Of Pharmaceutical Molecular Biology Graduate School Of Pharmaceutical Sciences Tohoku Uni
-
Mimaki Yoshihiro
Lab. Of Medicinal Plant Sci. School Of Pharmacy Tokyo Univ. Of Pharmacy And Life Sci. Jpn
-
Mimaki Yoshihiro
Laboratory Of Medical Plant Science Tokyo University Of Pharmacy And Life Science
-
Murata Kiyoshi
Japan Royal Jelly (jrj) Co. Ltd.
-
YAMAGUCHI Kikuji
Japan Royal Jelly (JRJ) Co. Ltd.
-
HITOMI Nobuyuki
Japan Royal Jelly (JRJ) Co. Ltd.
-
Ohizumi Yasushi
Univ. Shizuoka Shizuoka Jpn
-
Ohizumi Yasushi
Department Of Pharmaceutical Molecular Biology Faculty Of Pharmaceutical Sciences Tohoku University
-
Sakamoto Masahiro
Department Of Physiology Toho University School Of Medicine
-
Fujiwara Hironori
Department Of Pharmaceutical Molecular Biology Graduate School Of Pharmaceutical Sciences Tohoku Uni
-
Kogure Ako
Department of Anti-dementia Functional Food Development, Graduate School of Engineering, Tohoku Univ
-
Yamakuni Tohru
Laboratory of Pharmacotherapy, Graduate School of Pharmaceutical Sciences, Tohoku University, Japan
-
Yamaguchi Kikuji
Department of Anti-dementia Functional Food Development, Graduate School of Engineering, Tohoku Univ
-
Kogure Ako
Department Of Anti-dementia Functional Food Development Graduate School Of Engineering Tohoku Univer
-
Ohizumi Yasushi
Department Of Anti-dementia Functional Food Development Graduate School Of Engineering Tohoku Univer
-
Yamaguchi Kikuji
Department Of Anti-dementia Functional Food Development Graduate School Of Engineering Tohoku Univer
-
Sakamoto Masahiro
Department Of Anti-dementia Functional Food Development Graduate School Of Engineering Tohoku Univer
-
Ohizumi Yasushi
Department Of Pharmaceutical Molecular Biology Graduate School Of Pharmaceutical Sciences Tohoku Uni
-
Fujiwara Hironori
Department Of Anti-dementia Functional Food Development Graduate School Of Engineering Tohoku University
関連論文
- Furostanol glycosides from the rhizomes of Helleborus orientalis
- 海馬スライスにおいてPKA依存的シグナル伝達を促進する nobiletin はAβ誘発性記憶障害を改善する
- 柑橘類成分F-1の記憶・学習障害改善作用とそのメカニズム
- 海馬スライスにおける陳皮成分 nobiletin のLTP誘導作用
- CREBを活性化するノビレチンはNMDA受容体遮断薬により誘発される記憶・学習障害を改善する
- 56(P-23) Enterolobium contortisiliquumより単離された新規トリテルペン配糖体の構造とそれらのマクロファージに対する細胞毒性活性(ポスター発表の部)
- ヒガンバナ科アルカロイド, リコリン及びリコリシジノールによる炎症性サイトカイン, TNF-α産生の阻害
- 77(P-71) Securidaca inappendiculataより単離されたマクロファージ細胞死誘導活性物質の構造(ポスター発表の部)
- ヒメハギ科センヨクトウ (蝉翼藤) 由来サポニンのマクロファージに選択的な細胞死誘導作用 : 免疫・アレルギー (3)
- 神経栄養因子活性を有する天然生理活性物の探索とアルツハイマー病治療薬開発への応用
- ICRマウスの抗-DNPモノクローナルIgE抗体感作動物モデルにおけるノビレチンの皮膚炎および〓痒に対する効果
- 89(P26) Galtonia candicansより単離されたコレスタン配糖体の構造とそれらの培養腫瘍細胞に対する増殖抑制活性(ポスター発表の部)
- P-12 ブラジル産伝承生薬Stryphnodendron fissuratum,Ateleia glaziovianaに含有される化学成分と細胞毒性活性(ポスター発表の部)
- 125(P-84) 和漢薬「蒟蒻薯(Tacca chantrieriの根茎)」の化学成分と細胞毒性活性(ポスター発表の部)
- Steroidal Saponins from the Underground Parts of Hosta longipes and Their Inhibitory Activity on Tumor Promoter-Induced Phospholipid Metabolism
- Structures of Steroidal Saponins from the Tubers of Brodiaea californica and Their Inhibitory Activity on Tumor Promoter-Induced Phospholipid Metabolism
- Inhibitory Effects of Steroidal Saponins on 12-O-Tetradecanoylphorbol-13-acetate (TPA)-Enhanced ^P-Incorporation into Phospholipids of HeLa Cells and Proliferation of Human Malignant Tumor Cells
- Three New Cholestane Bisdesmosides from Nolina recurvata Stems and Their Inhibitory Activity on cAMP Phosphodiesterase and Na^+/K^+ ATPase
- Steroidal Constituents from the Underground Parts of Reineckea carnea and Their Inhibitory Activity on cAMP Phosphodiesterase
- P-27 甘草(Glycyrrhiza glabra L.)抽出物のPPAR-γリガンド活性成分の探索と抗糖尿活性(ポスター発表の部)
- Three New Furostanol Saponins from the Bulbs of Ipheion uniflorum
- New Steroidal Saponins from the Bulbs of Allium giganteum Exhibiting Potent Inhibition of cAMP Phosphodiesterase Activity
- 50(P-15) 甘草抽出物の抗糖尿病および抗内臓肥満活性とPPAR-γリガンド活性を指標とした活性成分の検索(ポスター発表の部)
- 機能性ハーブの生理活性に関する研究 Black Cohoshの抗ストレス作用について (第14回天然薬物の開発と応用シンポジウム 講演要旨集) -- (一般講演 機能性食品開発への新しいアプローチ)
- 63(P-20) Ornithogalum thyrsoidesより単離されたOSW-1類縁化合物の構造とそれらの腫瘍細胞に対する増殖抑制活性(ポスター発表の部)
- New Polyhydroxylated Steroidal Sapogenin and Saponin from the Leaves of Cestrum sendtenerianum
- P-19 Allium karatavienseおよびEranthis cilicicaより単離された新規高極性ステロイドならびにトリテルペン配糖体の化学構造に関する研究(ポスター発表の部)
- ユリ科クロユリ鱗茎の配糖体成分 (食品薬学シンポジウム講演要旨集)
- 高等植物からの新規医薬品シードの探索 (第16回 天然薬物の開発と応用シンポジウム講演要旨集) -- (シンポジウム3 医薬シーズ開発を志向した植物成分研究の新展開)
- 簡便な植物色素の分析法と〔東京薬科大学〕薬学部生薬系植物学実習での実践
- A NOVEL 16,23-EPOXY-5β-CHOLESTANE GLYCOSIDE WITH POTENT INHIBITORY ACTIVITY ON PROLIFERATION OF HUMAN PERIPHERAL BLOOD LYMPHOCYTES FROM ORNITHOGALUM SAUNDERSIAE BULBS
- A NOVEL HEXAHYDRODIBENZOFURAN DERIVATIVE WITH POTENT INHIBITORY ACTIVITY ON MELANIN BIOSYNTHESIS OF CULTURED B-16 MELANOMA CELLS FROM LINDERA UMBELLATA BARK
- Protective Activity of Geranium Oil and Its Component, Geraniol, in Combination with Vaginal Washing against Vaginal Candidiasis in Mice(Microbiology)
- Evaluation of the effect of terpenoid quinones on Trichophyton mentagrophytes by solution and vapor contact
- Suppressive Activity of Lycoricidinol (Narciclasine) against Cytotoxicity of Neutrophil-Derived Calprotectin, and Its Suppressive Effect on Rat A djuvant Arthritis Model
- Anti-Candida Activity of Calprotectin in Combination with Neutrophils or Lactoferrin
- Kinetical Analysis of Tumor Cell Death-Inducing Mechanism by Polymorphonuclear Leukocyte-Derived Calprotectin: Involvement of Protein Synthesis and Generation of Reactive Oxygen Species in Target Cells
- Convallasaponin A, a New 5β-Spirostanol Triglycoside from the Rhizomes of Convallaria majalis
- Four New Steroidal Saponins from the Rhizomes of Helleborus orientalis
- Norlanostane and Lanostane Glycosides from the Bulbs of Chionodoxa luciliae and Their Cytotoxic Activity
- Cycloartane Glycosides from the Rhizomes of Cimicifuga racemosa and Their Cytotoxic Activities
- Five New Triterpene Glycosides from Centella asiatica
- Steroidal Glycosides from the Bulbs of Camassia leichtlinii and Their Cytotoxic Activities
- Structures of Toxic Steroidal Saponins from Narthecium asiaticum MAXIM.
- Nobiletin, a Citrus Flavonoid That Improves Memory Impairment, Rescues Bulbectomy-Induced Cholinergic Neurodegeneration in Mice
- Triterpene Glycosides from the Stems of Akebia quinata
- Sesquiterpenoids and Flavonoids from the Aerial Parts of Tithonia diversifolia and Their Cytotoxic Activity
- Triterpenes and Triterpene Saponins from the Stems of Akebia trifoliata
- Cytotoxic Activities and Structure-Cytotoxic Relationships of Steroidal Saponins
- Cholestane Glycosides from the Bulbs of Galtonia candicans and Their Cytotoxicity
- Steroidal Saponins from the Bulbs of Allium karataviense
- Steroidal Saponins from the Bulbs of Allium ampeloprasum
- A New Furostanol Saponin with Six Sugars from the Bulbs of Allium sphaerosephalon Structural Elucidation by Modern NMR Techniques
- Inhibitory Effect of Mao-Bushi-Saishin-to on Prostaglandin E_2 Synthesis in C6 Rat Glioma Cells(Pharmacology)
- Ephedrae herba in Mao-Bushi-Saishin-To Inhibits IgE-Mediated Histamine Release and Increases cAMP Content in RBL-2H3 Cells
- A Novel Diol-derivative of Chalcone Produced by Bioconversion, 3-(2,3-Dihydroxyphenyl)-1-phenylpropan-1-one, Activates Phosphorylation of ERK and CREB in Cultured Rat Cortical Neurons
- Ephedrae herba (Mao) decreased histamine content in RBL-2H3 cells
- Characterization of Mechanisms of Fluconazole Resistance in a Candida albicans Isolate from a Japanese Patient with Chronic Mucocutaneous Candidiasis
- Proliferation of Intracellular Structure Corresponding to Reduced Affinity of Fluconazole for Cytochrome P-450 in Two Low-Susceptibility Strains of Candida albicans Isolated from a Japanese AIDS Patient
- Clerodane Diterpenoids and Flavonoids with NGF-Potentiating Activity from the Aerial Parts of Baccharis gaudichaudiana
- Prenylated Xanthones from Garcinia xanthochymus
- A New Iridoid Glycoside with Nerve Growth Factor-Potentiating Activity, Gelsemiol 6'-trans-Caffeoyl-1-glucoside, from Verbena littoralis
- Triterpene Glycosides from the Tubers of Anemone coronaria
- New Steroidal Glycosides from Rhizomes of Clintonia udensis
- A Novel Polyoxygenated Spirostanol Trisdesmoside from the Rhizomes of Helleborus orientalis
- Iridoids and Sesquiterpenoids with NGF-Potentiating Activity from the Rhizomes and Roots of Valeriana fauriei
- Taccasterosides A-C, Novel C_-Sterol Oligoglucosides from the Rhizomes of Tacca chantrieri(Communication to the Editor)
- Two New Steroidal Glycosides from Tacca chantrieri
- Four New 3,5-Cyclosteroidal Saponins from Dracaena surculosa
- 本学[東京薬科大学]薬学部における漢方薬物学実習の実施概要
- 蒟蒻薯(タシロイモ科植物Tacca chantrieriの根茎)の化学成分 (食品薬学シンポジウム講演要旨集)
- 天然素材からの新規機能性成分の探索 (シンポジウム:機能を持つ化粧品の有用性を支える技術)
- Sesquiterpene Esters from the Fruits of Celastrus orbiculatus
- PPARγリガンド活性を指標としたハーブのメタボリックシンドローム予防・改善作用の解明 (特集 ハーブ療法のサイエンスとエビデンスの構築に向けて)
- ハーブのα-グルコシダーゼおよびキサンチンオキシダーゼ阻害活性によるメタボリックシンドローム予防・改善作用の解明 (特集 ハーブ療法のサイエンスとエビデンスの構築に向けて)
- タシロイモ科植物Tacca chantrieriの化学成分と細胞毒性活性 (第14回天然薬物の開発と応用シンポジウム 講演要旨集) -- (一般講演 天然資源と医薬品開発1)
- Furostanol glycosides from the rhizomes of Helleborus orientalis
- Honeybee Royal Jelly Stimulates CRE-mediated Transcription in a PKA- but Not MEK/ERK-dependent Manner in PC12D Cells
- New Steroidal Glycosides from Rhizomes of Clintonia udensis
- Shishihakuhito, a Kampo Medicine for Atopic Dermatitis, Prevents Lipopolysaccharide-induced Activation of NF-κB-dependent Transcription in C6 Rat Glioma Cells
- Ephedorae herba Decreases Lipopolysaccharide-Induced Cyclooxgenase-2 Protein Expression and NF-κB-Dependent Transcription in C6 Rat Glioma Cells
- Neuroprotective Kaurane Diterpenes from Fritillaria ebeiensis
- Xanthones with NGF-potentiating activity
- Flavonoid Glycosides from Cecropia adenopus
- Triterpenoids from Rosa multiflora(Natural Medicine Note)
- Chemical Constituents from Dioscorea delicata(Natural Medicine Note)
- Triterpene Saponins from the Leaves of Sesbania sesban(Natural Medicine Note)
- Cytotoxic Alkaloids from the Barks of Ochrosia elliptica(Natural Medicine Note)
- Two New Steroidal Glycosides from Tacca chantrieri
- Five New Triterpene Glycosides from Centella asiatica
- Polymethoxylated Flavonoids from the Peels of Citrus depressa(Natural Medicine Note)
- Steroidal Saponins from the Bulbs of Allium ampeloprasum
- Steroidal Saponins from the Bulbs of Allium aflatunense
- Honeybee Royal Jelly and Nobiletin Stimulate CRE-Mediated Transcription in ERK-Independent and -Dependent Fashions, Respectively, in PC12D Cells
- Inhibitory Effects of Citrus Polymethoxyflavones, Nobiletin and its Analogues, on Acetylcholinesterase Activity
- The property of active substance from royal jelly in CRE-mediated transcriptional activity
- Isolation, Structural Elucidation, and Neuroprotective Effects of Iridoids from Valeriana jatamansi
- Liquid Chromatographic-Fluorometric Analysis of Paralytic Shellfish Toxins
- Structures of Two Paralytic Shellfish Toxins, Gonyautoxins V and VI, Isolated from a Tropical Dinoflagellate, Pyrodinium bahamense var. compressa
- Isolation and Structural Elucidation of Hemolysin from the Phytoflagellate Prymnesium parvum