A Case Report of a Cerebellar Neuroblastoma in a p53 Null Mutation Mouse(Pathology)
スポンサーリンク
概要
- 論文の詳細を見る
We report a case of cerebellar neuroblastoma in a 19-week-old p53 null mutation mouse. A white and soft mass was observed at the cerebellar vermis. Histologically, the tumor consisted of solid growth of round to oval pleomorphic cells with frequent mitotic figures. While there were no typical cellular arrangements of embryonic neurogenic tumors, such as Homer-Wright rosette, perivascular pseudorosette, or streaming of neoplastic neurocytes, small populations of the neoplastic cells were immunohistochemically positive for synaptophysin, microtubule-associated protein 2, S-100 and nestin. Both glial fibrillary acidic protein and vimentin were entirely negative in the neoplastic cells. Based on the biological characteristics of neoplastic cells, this tumor was diagnosed as neuroblastoma of the cerebellar origin.
- 社団法人日本獣医学会の論文
- 2009-03-25
著者
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SAEGUSA Yukie
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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SHIBUTANI Makoto
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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MITSUMORI Kunitoshi
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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Mitsumori Kunitoshi
Laboratory Of Veterinary Pathology Tokyo University Of Agriculture And Technology
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Mitsumori Kunitoshi
東京大学医科学研究所 癌細胞シグナル分野
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Mitsumori Kunitoshi
国立医薬品食品衛生研究所 病理部
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Mitsumori K
Laboratory Of Veterinary Pathology Tokyo University Of Agriculture And Technology
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三森 国敏
Laboratory Of Veterinary Pathology Tokyo University Of Agriculture And Technology
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TANIAI Eriko
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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AGO Kyohei
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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SHIMA Tomomi
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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Maita K
The Institute Of Environmental Toxicology:agrotox Inc.
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Mitsumori Kunitoshi
Department Of Pathology National Institute Of Health Sciences
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Mitsumori Kunitoshi
Laboratory Of Veterinary Pathology Division Of Animal Science Institute Of Symbiotic Science And Tec
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Ago Kyohei
Laboratory Of Veterinary Pathology Tokyo University Of Agriculture And Technology
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Shima Tomomi
Laboratory Of Veterinary Pathology Tokyo University Of Agriculture And Technology
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Taniai Eriko
Laboratory Of Veterinary Pathology Tokyo University Of Agriculture And Technology
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Saegusa Yukie
Laboratory Of Veterinary Pathology Tokyo University Of Agriculture And Technology
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Shibutani Makoto
Laboratory Of Veterinary Pathology Tokyo University Of Agriculture And Technology
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Shibutani Makoto
Division Of Pathology National Institute Of Health Sciences
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三森 国敏
Division Of Pathology National Institute Of Health Sciences
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Matsumoto K
Laboratory Of Veterinary Pathology Tokyo University Of Agriculture And Technology
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