A Case Report of an Uncommon Sex-Cord Stromal Tumor consisted of Luteal and Sertoli Cells in a Spayed Bitch
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概要
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We report a rare case of benign sex cord-stromal tumor consisted largely of luteoma with minor portion of Sertoli cell tumor located at the position of the left ovary excision in an 11-year-old ovariectomized bitch. Granulosa cell component was lacking, and both luteal and Sertoli cell portions were entirely positive for inhibin α and neuron-specific enolase, whereas luteoma portion alone was positive for Wilms’ tumor-1 (WT1), immunohistochemically. The results suggest that this tumor is a possible complication of incomplete ovarian excision at the time of ovariectomy and consisted of uncommon hybrid of luteal and Sertoli cells to be diagnosed as an unclassified sex cord-stromal tumor as applied in human cases. WT1-expression pattern suggested the signature of the difference in the phenotype of these cell types.
著者
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SHIBUTANI Makoto
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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MITSUMORI Kunitoshi
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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Ichimura Ryohei
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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Mizukami Sayaka
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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SUZUKI Terumasa
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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SHIMADA Yuko
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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Mitsumori Kunitoshi
Laboratory Of Veterinary Pathology Division Of Animal Science Institute Of Symbiotic Science And Tec
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Shibutani Makoto
Laboratory Of Veterinary Pathology Tokyo University Of Agriculture And Technology
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