Nutritional Efficiency of Nicotinamide N-Oxide and N'-Methylnicotinamide as Niacin in Rats(Food & Nutrition)
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概要
- 論文の詳細を見る
The nutritional efficiency of nicotinamide N-oxide and N'-methylmcotinamide as substitutes for nicotinic acid was investigated using weanling rats fed with a nicotinic acid-free and tryptophan-limited diet (basal diet; negative control), the basal diet containing 0.003% nicotinic acid (positive control), or basal diet containing various amounts of nicotinamide N-oxide or N'-methylnicotinamide. The relative niacin activity of nicotinamide N-oxide and N'-methylnicotinamide to nicotinic acid was about 1/5 and 1/2 on a weight basis, respectively, judged from the following comparisons: body weight gain, food intake, food efficiency ratio, the NAD contents in liver and blood, the total nicotinamide content in liver, and the urinary excretion of nicotinamide and its metabolites such as N^1-methylnicotinamide, N^1-methyl-2-pyridone-5-carboxamide, and N^1-methyl-4-pyridone-3-carboxamide.
- 社団法人日本農芸化学会の論文
- 1991-10-23
著者
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SHIBATA Katsumi
Department of Food Science and Nutrition, School of Human Cultures, The University of Shiga Prefectu
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Mori Y
Department Of Food Science And Nutrition Teikoku Women's University
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Mori Yuko
Department Of Biopharmaceutics Meiji Pharmaceutical University
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Shibata Katsumi
Department Of Food Science And Nutrition School Of Human Cultures The University Of Shiga Prefecture
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ONODERA Michiko
Department of Human Health Science, Faculty of Human Sciences, Osaka International University for Wo
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Onodera Michiko
Department Of Food Science And Nutrition Teikoku Women's University
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