Opioid Peptides from Milk Proteins
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概要
- 論文の詳細を見る
Fragment peptides of milk proteins containing Tyr-X-Phe or Tyr-X1-X2-Phe were synthesized and their opioid activities were evaluated by the guinea pig ileum and radioreceptor assays. Among the peptides tested, the human β-casein(51 - 54) amide, Tyr-Pro-Phe-Val-NH2 (valmuceptin) was the most active, more than the bovine counterpart, morphiceptin. The human β-casein(41 - 44) amide, Tyr-Pro-Ser-Phe-NH2, and the α-lactalbumin (50-53) amide, Tyr-Gly-Leu-Phe-NH2, were also active in the guinea pig ileum assay. These were named β-casorphin and α-lactorphin, respectively. All of these peptides were not as active in the mouse and rabbit vas deferens assays.
- 社団法人日本農芸化学会の論文
- 1986-09-23
著者
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YOSHIMURA Takashi
Department of Chemistry, Graduate School of Science, Osaka University
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Tani Fumito
Department Of Food Science And Technology Faculty Of Agriculture Kyoto University
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Tani Fumito
Research Institute For Food Science Kyoto University
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Tani F
Institute For Fundamental Research Of Organic Chemistry Kyushu University
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Fumito Tani
Division Of Food Science And Biotechnology Graduate School Of Agriculture Kyoto University
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Tani F
Institute For Materials Chemistry And Engineering Kyushu University
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Tani Fumito
Laboratory Of Food And Environmental Sciences Division Of Food Science And Biotechnology Graduate Sc
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Tani Fumito
Institute For Materials Chemistry And Engineering Kyushu University
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CHIBA Hideo
Department of Food Science and Technology, Faculty of Agriculture, Kyoto University
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YOSHIKAWA Masaaki
Department of Food Science and Technology, Faculty of Agriculture, Kyoto University
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Chiba H
Department Of Food Science And Technology Faculty Of Agriculture Kyoto University:(present Office)la
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Yoshikawa M
Himeji Inst. Technology Hyogo Jpn
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Yoshikawa Masaaki
Department Of Clinical Pharmacology School Of Medicine Tokai University
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Yoshimura Takashi
Department Of Chemistry Graduate School Of Science Osaka University
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Yoshimura Takashi
Department Of Chemistry Faculty Of Engineering Gunma University
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