1108 極微細ヒータを用いた生体分子モータの回転速度制御 : バイオ機能分子と無機微細加工構造物に融合による新機能素子の創造に向けて(要旨講演,マイクロメカトロニクス)

概要

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The method for rapid and reversible motion control of a single biomolecular motor is a key technology for future goal of integrating biomoletular motors with organic-inorganic hybrid nanosystems. A device for controlling the temperature locally under the microscope with fast response, 71.5K/s and 56.9K/s for temperature rise and fall respectively, was manufactured. Rapid and reversible angular velocity control of a single F1-ATPase, a rotary biomolecular motor, was achieved by switching the temperature. The rotation assay at the temperature higher than around 50℃ was realized thanks to the rapid switching of the temperature. The torque of F1-ATPase was found to increase at higher temperature by subtracting the effect of viscous drag of water.
一般社団法人日本機械学会の論文
2005-03-21