MNM-P9-2 細胞間相互作用解析のための異種細胞隣接配置ダイナミックマイクロアレイの作製(P9 マイクロ・ナノスケールバイオ計測と医用応用)

概要

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In this study, we propose a dynamic microarray device that can pair two different types of cells. Microchannels in the device are composed of three parts : a trapping site, a trapping channel and a bypassing channel. By introducing cells cultured onto the hydrogel beads into the microchannels, we can make an array of paired two different types of cells in trapping sites. Besides, we fabricated the microplates for handling single cells. Introduction of the microplates into the microchannels can be applied to pair different types of single cells and analyze cell-cell interaction. We expect that this method will be useful in the continuous observation of the interaction or molecular diffusion between two types of cells.
一般社団法人日本機械学会の論文
2010-10-12