長期透析者の肝炎管理

概要

論文の詳細を見る
Hepatitis resulting from administration of blood has been and is a great problem in patients and staff of hemodialysis units. The risk of post-transfusion hepatitis has been reported to be as low as 2.3% and as high as 66.7% in patients underwent long-term intermittent hemodialysis. The artificial-kidney center at Kitasato University Hospital has been in operation since July, 1971 and there were one fatal and eight non-fatal cases of hepatitis in 89 uremic patients who underwent a total of 4162 hemodialysis. It is found by Blumberg, Prince, Okochi and others that Au-antigen is closely associated with viral hepatitis and it has been also reported that the uremic patients with hepatitis have high incidence of positive Au-antigen. Since there are no reliable measures to prevent viral hepatitis, the following items must be requested in taking care of uremic patients undergoing hemodialysis and staff of hemodialysis units as well. 1) Efforts to manage anemia without blood transfusion. If needed, frozen blood is recommended. 2) Frequent check of liver function, especially SGPT and SGOT. In addition, Au-anti-gen should be checked at least every two months. 3) Efforts to keep good general hygiene in hemodialysis unit.
北里大学の論文
1974-06-30