溶解補助剤の研究(第2報) : グリコール類およびその誘導体と水との混液の性質について
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概要
- 論文の詳細を見る
Physical constants, i.e. surface tension, partial specific volume, reduced viscosity, and refractive index, were measured with a mixture of 10 kind of solubilizing agent and water. Mixed solutions of having only hydrophilic group, ethylene glycol, diethylene glycol, triethylene glycol with water did not show a break in the foregoing physical properties and these stubstances were considered not to undergo association. On the other hand, substances having both hydrophobic and hydrophilic groups, such as cellosolve, butylcellosolve, carbitol, butylcarbitol, hexylene glycol, dipropylene glycol and diethylin with water showed a break in physical properties, suggesting that association occurred in these mixtures at a certain concentration of these substances, resulting in a sudden change in their internal structure. A mixed solutions of butylcellosolve, butylcarbitol, hexylene glycol, and diethylin with water showed a clear break point in physical properties suggesting that they are highly associated in the solution.
- 公益社団法人日本薬学会の論文
- 1970-10-25
著者
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加藤 百合子
Faculty Of Pharmaceutical Sciences Science University Of Tokyo
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加藤 百合子
東京理科大学薬学部
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佐藤 有希
東京理科大学薬学部
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