1-Azabicyclo化合物の研究(第20報)Hexahydroisoquino[3,2-c][1,4]benzodiazepineおよび関連化合物の合成ならびにHexahydroisoquino[3,2-c]-[1,4]benzodiazepin-13-one から6-Methyl-hexahydro-5H-dibenzo[b, g][1,5]diazacycloundecineの生成
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概要
- 論文の詳細を見る
Aminolactam (XIII), dilactam (XVII), and thiadiazepine (XXI) derivatives were synthesized by the intramolecular ring closure of the aminoesters (XI, XVI, XIX), respectively. Reduction of the methiodide (XXII) of XIIIa gave the eleven-membered lactam (XXX) in a good yield, which, on treatment with lithium aluminum hydride, was converted to the corresponding diamine (XXXI).
- 公益社団法人日本薬学会の論文
- 1974-08-25
著者
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加藤 日出男
北陸製薬株式会社
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越中 栄一
Research and Development Division, Hokuriku Seiyaku Co., Ltd.,
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越中 栄一
北陸製薬株式会社 中央研究所
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荒田 義雄
金沢大学薬学部
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越中 栄一
Research And Development Division Hokuriku Seiyaku Co. Ltd.
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荒田 義雄
Faculty Of Pharmaceutical Sciences Kanazawa University
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西川 公康
北陸製薬株式会社研究所
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- 臭化チキジウム
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