1-Azabicyclo化合物の研究(第25報)Octahydropyrrolo[1,2-α]pyrazin-1-oneから9員環状Aminolactamおよび関連化合物の合成
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Reduction of both methiodides, II and XI, with lithium in liquid ammonia or sodium amalgam gave nine-membered aminolactams, III and XII, respectively, which, on treatment with lithium aluminum hydride, afforded the correspouding diamines, IV and XIII. Diamines (IV and XIII) were also obtained by lithium aluminum hydride reduction of II and XI, respectively. Reduction of XV with lithium in liquid ammonia yielded XVI.
- 公益社団法人日本薬学会の論文
- 1975-07-25
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