各種環境汚染物質のヒメダカ(Oryzias latipes)に対する致死毒性に及ぼす細菌内毒素の影響

概要

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Lethal toxicity of endotoxin was observed on killifish (Oryzias latipes) at relatively high temperature (30℃). Effect of endotoxin on the lethal toxicity of various pollutants was examined for killifish at 30℃. Permissible volumes of various dissolvents with and without endotoxin were determined at 30℃. Ten percent diethylether-dimethysulfoxide solution was chosen as a suitable dissolvent for water-insoluble pollutants with and without endotoxin. Reared concentration of about 90 kinds of pollutants were decided previously to the acute toxicity test in the presence of endotoxin. Endotoxin increased the lethal toxicities of HgCl_2,NaSeO_4,MnCl_2,methanol, ethanol, propanol, butanol, pentanol, Span 60,Tween 60,ethylene glycol, propylene glycol and methyl cellosolve for killifish, and decreased the lethal toxicities of CuCl_2,CuSO_4,AgNO_3 and Cu (CH_3COO)_2.
社団法人日本薬学会の論文
1986-06-30