O-(N-Succinimidyl)-1,1,3,3-tetramethyluronium Tetrafluoroborate-N-Hydroxysuccinimide-CuCl_2 : A Facile and Reliable System for Racemization-Free Coupling of Peptides Havng a Carboxy-terminal N-Methylamino Acid
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概要
- 論文の詳細を見る
Simultaneous use of N-hydroxysuccinimide (HOSu) and CuCl_2 with a HOSu-based uronium coupling reagent, O-(N-succinimidyl)-1,1,3,3-tetramethyluronium tetrafluoroborate, has been found to eliminate the racemization of the carboxy-terminal N-methylamino acid residue during the segment condensation.
- 公益社団法人日本薬学会の論文
- 2000-03-01
著者
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Miura Tomisato
弘前大学 理工学研究科物質理工学
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Mori Tetsuya
Department Of Radiology And Nuclear Medicine Hyogo Brain And Heart Center
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Mori Tomonori
(present Address)faculty Of Engineering Towa University
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Mori T
First Institute Of New Drug Research Otsuka Pharmaceutical Co. Ltd.
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Ishizuka Sou
Department Of Industrial Chemistry Faculty Of Engineering Seikei University
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Kurita K
Department Of Applied Chemistry Faculty Of Engineering Seikei University
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Kurita Keisuke
Department Of Applied Chemistry Faculty Of Engineering Seikei University
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Kurita Keisuke
Department Of Materials And Life Science Faculty Of Science And Technology Seikei University
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Nishiyama Y
Department Of Pathology And Laboratory Medicine The University Of Texas-houston Medical School
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Nishiyama Yasuhiro
Department Of Applied Chemistry Osaka University
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Nishiyama Y
Department Of Natural Medicinal Chemistry Kobe Pharmaceutical University
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