Rat Small Intestine Muscle Relaxation Alkaloids from Orixa japonica Leaves
スポンサーリンク
概要
- 論文の詳細を見る
Two quinoline alkaloids, japonine (1) and eduline (2) were isolated from the methanol extract of the leaves of Orixa japonica as relaxants against rat small intestine muscle. The activity of these alkaloids was comparable to that of the typical muscle relaxant papaverine (4). This is also the first report of the isolation of eduline (2) from O. japonica.
- 公益社団法人日本薬学会の論文
- 2001-01-01
著者
-
Tanaka R
Kyushu Univ. Fukuoka Jpn
-
Mori Tetsuya
Osaka University Of Pharmaceutical Sciences
-
Murata K
Aoba Kasei Co. Ltd.
-
MORI Tetsuya
Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center
-
FUNAYAMA Shinji
Department of Kampo Pharmaceutical Sciences, Nihon Pharmaceutical University
-
Mori Tetsuya
Department Of Radiology And Nuclear Medicine Hyogo Brain And Heart Center
-
Murata Kiyoshi
Aoba Kasei Co. Ltd.
-
Noshita Toshiro
Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Aomori University
-
Tanaka Rioko
Department Of Bioscience And Biotechnology Aomori University
-
KUMEKAWA Yasuhiro
Department of Bioscience and Biotechnology, Aomori University
-
KASHIWAGURA Tadashi
Department of Bioscience and Biotechnology, Aomori University
-
Funayama S
Dep. Of Kampo Pharmaceutical Sciences Nihon Pharmaceutical Univ.
-
Funayama Shinji
Department Of Bioscience And Biotechnology
-
Noshita T
Dep. Of Life Sciences Fac. Of Life And Environmental Sciences Prefectural Univ. Of Hiroshima
-
Noshita Toshiro
Department Of Bioscience And Biotechnology
-
Kumekawa Yasuhiro
Department Of Bioscience And Biotechnology Aomori University
-
Kashiwagura Tadashi
Department Of Bioscience And Biotechnology Aomori University
-
Mori Tetsuya
Department Of Pediatrics Keio University School Of Medicine
関連論文
- Isolation of Ursolic Acid from Apple Peels and Its Specific Efficacy as a Potent Antitumor Agent
- Preparation of Dye-labeled Alginate for the Assay of Alginate Lyase
- Preparation of Two Series of Oligo-guluronic Acids from Sodium Alginate by Acid Hydrolysis and Enzymatic Degradation
- A Simple Method for Preparation of Poly-mannuronate Using Poly-guluronate Lyase
- Purification and Characterization of Extracellular Alginate Lyase from Enterobacter cloacae M-1
- Cytosolic acetyl-CoA synthetase affected tumor cell survival under hypoxia : the possible function in tumor acetyl-CoA/acetate metabolism
- Comparison of FDG-PET and IMP-SPECT in patients with dementia with Lewy bodies
- Antidiuretic Effects of a Novel Nonpeptide Vasopressin V_2-Receptor Agonist, OPC-51803, Administered Orally to Dogs
- Effects of OPC-51803, a Novel, Nonpeptide Vasopressin V_2-Receptor Agonist, on Micturition Frequency in Brattleboro and Aged Rats
- Biosynthesis of Quinolactacin A, a TNF Production Inhibitor
- Distinctive FDG and FES accumulation pattern of two tamoxifen-treated patients with endometrial hyperplasia
- Preparation of New Nitrogen-Bridged Heterocycles. 53. Syntheses of 3-(Benzylthio)thieno[3,4-b]indolizine Derivatives and Their Intramolecular Arene-Arene Interactions
- Cytotoxic Alkaloids of Pachysandra terminalis
- Cytocidal and Antimicrobial Activities of Flavonoids
- Genetic identification and detection of human pathogenic Rhizopus species, a major mucormycosis agent, by multiplex PCR based on internal transcribed spacer region of rRNA gene
- Casein Kinase II (CK-II)-Mediated Stimulation of HIV-1 Reverse Transcriptase Activity and Characterization of Selective Inhibitors in Vitro
- The Effects of (-)-Epigallocatechin-3-Gallate on the Proliferation and Differentiation of Human Megakaryocytic Progenitor Cells
- Variaion in FDG uptakes in different regions in normal human brain as a function of the time (30 and 60 mimutes) after injection o FDG
- Characterization of Fe(III)-Deferoxamine and Mn(II)-Pectin as Magnetic Resonance Imaging Contrast Agents
- Adxanthromycins A and B, New Inhibitors of ICAM-1/LFA-1 Mediated Cell Adhesion Molecule from Streptomyces sp. NA-148 : II. Physico-chemical Properties and Structure Elucidation
- Biochemical Characterization of 60S Acidic Ribosomal P Proteins Associated with CK-II from Bamboo Shoots and Potent Inhibitors of Their Phosphorylation in Vitro
- Molecular cloning and functional expression in yeast of a trans-cinnamate-4-hydroxylase from Melianthus comosus
- Quinolone-Resistant Mutations of DNA Gyrase Increase Sensitivity to Acriflavine
- GENE EXPRESSION AND LOCALIZATION OFPECTIN DEGRADING ENZYMES IN CARROT (DAUCAS CAROTA L.)
- Gene characterizations and biochemicalanalysis of carrot pectin degrading enzymes (α-L-arabinofuranosidase, exo-polygalacturonase)
- Application of Liquid Chromatography-Atmospheric Pressure Chemical Ionization Mass Spectrometry to the Differentiation of Stereoisomeric Diterpenoid Alkaloids
- Effect of Aconitum Alkaloid Kobusine and Pseudokobusine Derivatives on Cutaneous Blood Flow in Mice; II
- Application of Liquid Chromatography-Atmospheric Pressure Chemical Ionization Mass spectrometry to the Differentiation of Stereoisomeric C_-Norditerpenoid Alkaloids
- Effects of Aconitum Alkaloid Kobusine and Pseudokobusine Derivatives on Cutaneous Blood Flow in Mice
- Effects of Alkaloids from Aconitum yesoense var. macroyesoense on Cutaneous Blood Flow in Mice
- Total Synthesis of Natural (+)-Phomopsolide B, an Antifeedant against Elm Bark Beetle
- Total Synthesis of Natural (+)-Phomopsolide B(Organic Chemistry)
- Characterization of (-)-Matairesinol as a Potent Inhibitor of Casein Kinase I in Vitro
- Absolute Stereochemistry of (-)-Preorixine and Related Compounds
- Quinoline Alkaloids from Stems of Orixa japonica
- Evaluation of the Histamine H_1-Antagonist-Induced Place Preference in Rats
- Lysosomal Cysteine Protease, Cathepsin H, Is Targeted to Lysosomes by the Mannose 6-Phosphate-Independent System in Rat Hepatocytes
- Lysosomal Cystein Protease, Cathepsin B, Is Targeted to Lysosomes by the Mannose 6-Phosphate-Independent Pathway in Rat Hepatocytes: Site-Specific Phosphorylation in Oligosaccharides of the Proregion
- Rat Small Intestine Muscle Relaxation Alkaloids from Orixa japonica Leaves
- Effect of Oral OPC-28326, a Selective Femoral Arterial Vasodilator, on Hindlimb Subcutaneous Tissue Temperature in Conscious Dogs Under Buprenorphine Sedation
- Evaluation of Radioiodinated 1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(2-iodophenylpropyl)piperazine as a Tumor Diagnostic Agent with Functional Sigma Receptor Imaging by Single Photon Emission Computed Tomography(Pharmacology)
- In Vivo Evaluation of Radioiodinated 1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)-piperazine Derivatives as New Ligands for Sigma Receptor Imaging Using Single Photon Emission Computed Tomography(Pharmacology)
- Synthesis and in Vitro Evaluation of Iodinated Derivatives of Piperazine as a New Ligand for Sigma Receptor Imaging by Single Photon Emission Computed Tomography
- Glycyrrhetinic Acid Induces Anoikis-Like Death and Cytoskeletal Disruption in the Central Nervous System Tumorigenic Cells
- The Augmenting Activity of 6-(Methylsulfinyl) hexyl Isothiocyanate on Cellular Glutathione Levels Is Less Sensitive to Thiol Compounds Than Its Cytotoxic Activity
- New Cytotoxic Phenolic Derivatives from Matured Fruits of Magnolia denudata
- The Augmenting Activity of 6-(Methylsulfinyl)hexyl Isothiocyanate on Cellular Glutathione Levels Is Less Sensitive to Thiol Compounds Than Its Cytotoxic Activity
- Machilin G and Four Neolignans from Young Fruits of Magnolia denudata Show Various Degrees of Inhibitory Activity on Nitric Oxide (NO) Production
- Detection of 6-(Methylsulfinyl)hexyl Isothiocyanate (6-MITC) and Its Conjugate with N-Acetyl-L-cysteine (NAC) by High Performance Liquid Chromatograpy-Atmospheric Pressure Chemical Ionization Mass Spectrometry (HPLC-MS/APCI)
- Reinvestigation of Phenolic Ferrier Reaction : Selective Synthesis of Aryl O-Δ^2-Glycosides
- New Quinoline Alkaloids from the Leaves and Stems of Orixa japonica, Orijanone, Isopteleflorine and 3'-O-Methylorixine
- Quinoline Alkaloids of Orixa japonica
- O-(N-Succinimidyl)-1,1,3,3-tetramethyluronium Tetrafluoroborate-N-Hydroxysuccinimide-CuCl_2 : A Facile and Reliable System for Racemization-Free Coupling of Peptides Havng a Carboxy-terminal N-Methylamino Acid
- A Racemization-Free Coupling Method for Peptides Having N-Methylamino Acids at the Carboxy-Termini
- Preparation of Nonnatural Branched Chitin and Chitosan
- Isolation of Hippadine from the Roots of Lycoris radiata
- Isolation of (-)-4'-demethyl traxillagenin from Thujopsis dolabrata Sieb. et Zucc. var. hondai Makino
- Anti-influenza virus principles from Muehlenbeckia hastulata
- Cytocidal Principle and Aporphine Alkaloids of Nandina domestica Root-barks(Natural Medicine Note)
- Quinoline Alkaloids from Stems of Orixa japonica(Natural Medicine Note)
- Cytocidal and Antimicrobial Activities of Flavonoids
- Isolation of ethyl caffeate from the petals of Prunus yedoensis
- Structure-activity relationships and the cytotoxic effects of novel diterpenoid alkaloid derivatives against A549 human lung carcinoma cells
- Isolation of Hippadine from the Roots of Lycoris radiata(Natural Medicine Note)