Cytotoxic C-Benzylated Dihydrochalcones from Uvaria acuminata

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概要

• 論文の詳細を見る

• Two new C-benzylated dihydrochalcones, isochamuvaritin (1) and acumitin (2), have been isolated from the African medicinal plant Uvaria acuminata, together with the previously reported benzylbenzoate (3), uvaretin (4), isouvaretin (5), diuvaretin (6), and uvangoletin (7). The structural elucidation of compounds 1 and 2 in spectroscopic studies is described. C-Benzylated dihydrochalcones, especially 1,2,4, and 6, showed considerable cytotoxicity toward human promyelocytic leukemia HL-60 cells.

• 公益社団法人日本薬学会の論文
• 2004-01-01

著者

• Kato A

  Natural Medicinal Chemistry Kobe Pharmaceutical University

• KATO Atsushi

  Department of Hostpital Pharmacy, Graduate School of Medicine and Pharmaceutical Sciences, Universit

• Kato Atsushi

  Department Of General Surgery Chiba University Graduate School Of Medicine

• TAKAHASHI TOMOKO

  Department of Cancer Cytogenetics, Division of Molecular Biology, Research Institute for Radiation B

• Mathenge S

  Department Of Botany University Of Nairobi

• JUMA Francis

  Department of Clinical Pharmacology, Kenyatta National Hospital, University of Nairobi

• MATHENGE Simon

  Department of Botany, University of Nairobi

• ICHIMARU Momoyo

  Department of Natural Medicinal Chemistry, Kobe Pharmaceutical University

• NAKATANI Noriyoshi

  Department of Natural Medicinal Chemistry, Kobe Pharmaceutical University

• NISHIYAMA Yumi

  Department of Natural Medicinal Chemistry, Kobe Pharmaceutical University

• MORIYASU Masataka

  Department of Natural Medicinal Chemistry, Kobe Pharmaceutical University

• NGANGA Joseph

  Department of Medicine, University of Nairobi

• Juma F

  Department Of Clinical Pharmacology Kenyatta National Hospital University Of Nairobi

• Nganga J

  Department Of Medicine University Of Nairobi

• Tamura T

  Department Of Natural Medicinal Chemistry Kobe Pharmaceutical University

• Nishiyama Y

  Department Of Natural Medicinal Chemistry Kobe Pharmaceutical University

• Ichimaru M

  Department Of Natural Medicinal Chemistry Kobe Pharmaceutical University

• Mathenge Simon

  Department Of Botany University Of Nairobi

• Moriyasu Masataka

  Department Of Natural Medicinal Chemistry Kobe Pharmaceutical University

• Moriyasu M

  Department Of Natural Medicinal Chemistry Kobe Pharmaceutical University

• Moriyasu Masataka

  Institute Of Pharmacognosy Kobe Women's College Of Pharmacy

• Nakatani Noriyoshi

  Department Of Natural Medicinal Chemistry Kobe Pharmaceutical University

• Takahashi Tomoko

  Department Of Cancer Cytogenetics Division Of Molecular Biology Research Institute For Radiation Bio

• Kato Atsushi

  Department Of Biological Science Graduate School Of Life And Environment Science Shimane University

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