Interdigitating Cell Sarcoma-A report of an autopsy case and literature review-:—A report of an autopsy case and literature review—
スポンサーリンク
概要
- 論文の詳細を見る
A 58-year-old Japanese man developed discomfort of his left neck, gradually increasing left chest pain, and weight loss (15 kg over six months). His primary physician noted generalized lymphadenopathy, and a neck lymph node was excised for diagnosis. When he was admitted to our hospital, he had severely decreased appetite accompanied by a large intra-abdominal mass. The lymphadenopathy was temporarily reduced by CHOP (cyclophosphamide, hydroxydoxorubicin/adriamycin, vincristine/oncovin, prednisone) chemotherapy, but pancytopenia and hepatomegaly persisted. After 3 courses of therapy, tumor cell regrowth was evident in peripheral blood and bone marrow and his course rapidly declined, with complications from hemophagocytic syndrome. He expired after a total course of 6 months. A postmortem examination was performed 2 hours after death. A final diagnosis of interdigitating cell sarcoma was made based on histological and immunohistochemical analyses of the biopsied lymph nodes and autopsy materials. His clinical course was extremely aggressive, and chemotherapy was not effective. Discussion of this case provides important insight into the clinicopathological features and treatment of this neoplasm.
- 日本リンパ網内系学会の論文
著者
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Harada Yuko
Department Of Biology Faculty Of Science Kyushu University
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Wada Kiriko
Department Of Neurology Hematology Metabolism Endocrinology And Diabetology (dnhmed) Yamagata Univer
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Maeda Kunihiko
Department Of Pathology Yamagata University School Of Medicine
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Tajima Katsushi
Department Of Neurology Hematology Metabolism Endocrinology And Diabetology Faculty Of Medicine Yama
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Takahashi Tomoko
Department Of Cancer Cytogenetics Division Of Molecular Biology Research Institute For Radiation Bio
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Watarai Keiko
Department of Pathology, Yamagata University School of Medicine
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Yamakawa Mitsunori
Department of Pathological Diagnostics Faculty of Medicine, Yamagata University
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Harada Yuko
Department of Neurology, Hematology, Metabolism, Endocrinology and Diabetes, Yamagata University School of Medicine
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Saitoh Chihiro
Department of Pathology, Yamagata University School of Medicine
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Hiroshima Yuki
Department of Neurology, Hematology, Metabolism, Endocrinology and Diabetes, Yamagata University School of Medicine
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Wada Kiriko
Department of Pathology, Yamagata University School of Medicine
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