A Tolerance Gene for Prenylated Flavonoid Encodes a 26S Proteasome Regulatory Subunit in Sophora flavescens
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概要
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Yeast functional screening with a Sophora flavescens cDNA library was performed to identify the genes involved in the tolerant mechanism to the self-producing prenylated flavonoid sophoraflavanone G (SFG). One cDNA, which conferred SFG tolerance, encoded a regulatory particle triple-A ATPase 2 (SfRPT2), a member of the 26S proteasome subunit. The yeast transformant of SfRPT2 showed reduced SFG accumulation in the cells.
- 社団法人 日本農芸化学会の論文
著者
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Yazaki Kazufumi
Laboratory of Plant Gene Expression, Research Institute for Sustainable Humanosphere, Kyoto Universi
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MORIYASU Masataka
Department of Natural Medicinal Chemistry, Kobe Pharmaceutical University
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KAMIMOTO Yoshihisa
Laboratory of Plant Gene Expression, Research Institute for Sustainable Humanosphere, Kyoto Universi
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Kamimoto Yoshihisa
Laboratory Of Plant Gene Expression Research Institute For Sustainable Humanosphere Kyoto University
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ITO Kozue
Department of Experimental Immunology, and the CREST Program of Japan Science and Technology Agency
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SHITAN Nobukazu
Department of Natural Medicinal Chemistry, Kobe Pharmaceutical University
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MINAMI Shota
Department of Natural Medicinal Chemistry, Kobe Pharmaceutical University
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KUBO Mizuki
Department of Natural Medicinal Chemistry, Kobe Pharmaceutical University
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