A Tolerance Gene for Prenylated Flavonoid Encodes a 26S Proteasome Regulatory Subunit in Sophora flavescens

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概要

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• Yeast functional screening with a Sophora flavescens cDNA library was performed to identify the genes involved in the tolerant mechanism to the self-producing prenylated flavonoid sophoraflavanone G (SFG). One cDNA, which conferred SFG tolerance, encoded a regulatory particle triple-A ATPase 2 (SfRPT2), a member of the 26S proteasome subunit. The yeast transformant of SfRPT2 showed reduced SFG accumulation in the cells.

• 社団法人 日本農芸化学会の論文
• 2011-05-23

著者

• Yazaki Kazufumi

  Kyoto Univ. Kyoto Jpn

• Yazaki Kazufumi

  Lab. Of Plant Gene Expression Res. Inst. For Sustainable Humanosphere Kyoto Univ.

• Yazaki Kazufumi

  Laboratory Of Gene Expression Wood Research Institute Kyoto University

• MORIYASU Masataka

  Department of Natural Medicinal Chemistry, Kobe Pharmaceutical University

• Kamimoto Yoshihisa

  Laboratory Of Plant Gene Expression Research Institute For Sustainable Humanosphere Kyoto University

• ITO Kozue

  Department of Experimental Immunology, and the CREST Program of Japan Science and Technology Agency

• SHITAN Nobukazu

  Department of Natural Medicinal Chemistry, Kobe Pharmaceutical University

• MINAMI Shota

  Department of Natural Medicinal Chemistry, Kobe Pharmaceutical University

• Kubo Mizuki

  Department Of Natural Medicinal Chemistry Kobe Pharmaceutical University

• Minami Shota

  Department Of Natural Medicinal Chemistry Kobe Pharmaceutical University

• Ito Kozue

  Department Of Natural Medicinal Chemistry Kobe Pharmaceutical University

• Ito Kozue

  Department Of Experimental Immunology And The Crest Program Of Japan Science And Technology Agency (

• Shitan Nobukazu

  Department Of Natural Medicinal Chemistry Kobe Pharmaceutical University

• Moriyasu Masataka

  Department Of Natural Medicinal Chemistry Kobe Pharmaceutical University

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