Semisynthetic β-Lactam Antibiotics. IV. The X-Ray Analysis of Monopotassium α-Sulfophenylacetate Monohydrate. The Configuration of the Acyl Side Chain of α-Sulfobenzylpenicillin
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概要
- 論文の詳細を見る
The absolute configuration of (-)-α-sulfophenylacetic acid (II), the side chain acid of a novel antipseudomonal semisynthetic penicillin, (-)-α-sulfobenzylpenicillin (I), has been determined and confirmed to be in the D-series. Accordingly, the biologically more active diastereoisomer which is derived from II has been assigned to be D(-)-α-sulfobenzylpenicillin.
- 公益社団法人日本薬学会の論文
- 1973-05-25
著者
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神谷 和秀
Central Research Division Takeda Chemical Industries Ltd.
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野村 容朗
Central Research Division, Takeda Chemical Ind., Ltd.,
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西川 正夫
Chemical Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.
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森本 至郎
Central Research Laboratories Takeda Chemical Industries Ltd.
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野村 容朗
Research and Development Division, Eisai Company, Ltd.,
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和田 喜一
Central Research Division, Takeda Chemical Industries, Ltd. Kusunoki-cho, Ikuta-ku, Kobe
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西川 正夫
Central Research Division, Takeda Chemical Industries, Ltd.
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野村 容朗
Research And Development Division Eisai Company Ltd.
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西川 正夫
Central Research Division Takeda Chemical Industries Ltd.
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Nomura Hiroaki
Research And Development Division Eisai Company Ltd.
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和田 喜一
Central Research Division Takeda Chemical Industries Ltd.
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