Studies on Pillaromycin A. V. The X-Ray Analysis of Pillaronone Monobromoacetate

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概要

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• In order to confirm the chemical and stereochemical structure of pillaronone, a derivative of the aglycone obtained from pillaromycin A, an X-ray analysis of its monobromoacetate has been carried out. Pillaronone monobromoacetate crystallizes in the orthorhombic system, space group P2_12_12_1-D^4_2,with four molecules of C_<22>H_<19>O_6Br in a unit cell. Application of a three-dimensional Patterson superposition method facilitated the elucidation of the structure which is given in formula (I). The final R-value was 0.133. The absolute configuration was determined using the anomalous dispersion of the bromine atom. The molecular structure in the crystal was also discussed.

• 公益社団法人日本薬学会の論文
• 1970-09-25

著者

• 神谷 和秀

  Central Research Division Takeda Chemical Industries Ltd.

• 西川 正夫

  Chemical Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.

• 水野 公明

  Research Laboratories, Takeda Chemical Industries., Ltd.

• 浅井 満子

  武田薬品中央研究所

• 新田 勇

  Faculty of Science, Kwansei Gakuin University

• 新田 勇

  Faculty Of Science Kwansei Gakuin University

• 西川 正夫

  Central Research Division Takeda Chemical Industries Ltd.

• 水野 公明

  Central Research Division, Takeda Chemical Industries, Ltd.

• 水野 公明

  Central Research Division Takeda Chemical Industries Ltd.

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