X-Ray Analysis of Thiamine Propyl Disulfide
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概要
- 論文の詳細を見る
The crystal structure of thiamine propyl disulfide (TPD) was determined by the three dimensional Patterson superposition method and by application of least squares treatment and Fourier syntheses. The unit cell is monoclinic, space group P2_1/a, with a=21.04,b=11.35,c=8.53 A and β=101°36'. The propyl disulfido group has been found to lie cis to the N-formyl group, the result being consistent with the hitherto proposed structure for TPD. The structure of the pyrimidine portion was discussed in comparison with the results of earlier workers. The stereochemical structure of TPD and a unique hydrogen bonding in the crystal were also discussed.
- 公益社団法人日本薬学会の論文
- 1969-05-25
著者
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神谷 和秀
Central Research Division Takeda Chemical Industries Ltd.
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西川 正夫
Chemical Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.
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朝日 豊
Chemical Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.
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神谷 和秀
Chemistry Research Laboratories Takeda Chemical Industries Ltd.
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松丸 秀夫
Chemical Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.
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西川 正夫
Central Research Division Takeda Chemical Industries Ltd.
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朝日 豊
Chemical Research Laboratories Central Research Division Takeda Chemical Industries Ltd.:(present Ad
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松丸 秀夫
Chemical Research Laboratories Research And Development Division Takeda Chemical Industries Ltd.
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