Studies on L-Ascorbic Acid Derivatives. VI. Phosphorylation of L-Ascorbic Acid and Its Isopropylidene Derivative
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概要
- 論文の詳細を見る
Phosphorylation of L-ascorbic acid and its 5,6-isopropylidene acetal with phosphoryl chloride under conditions using water as solvent and pyridine as base yielded almost quantitatively and selectively L-ascorbic acid 3-phosphate which has been a useful com-pound in cosmetic field. The reaction is suitable for manufacturing of the phosphate in a good yield. The effects of changes in solvent and base upon the phosphorylation reaction are also discussed by comparison of the yield and the composition of the products.
- 公益社団法人日本薬学会の論文
- 1971-07-25
著者
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森本 至郎
Central Research Laboratories Takeda Chemical Industries Ltd.
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野村 容朗
Research and Development Division, Eisai Company, Ltd.,
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野村 容朗
Research And Development Division Eisai Company Ltd.
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Nomura Hiroaki
Research And Development Division Eisai Company Ltd.
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下村 昌史
Research and Development Division, Takeda Chemical Industries, Ltd.
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森本 至郎
Research and Development Division, Takeda Chemical Industries, Ltd.
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下村 昌史
Research And Development Division Takeda Chemical Industries Ltd.
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