Metabolism of 4-Dimethylaminoazobenzene and Related Compounds. III. Metabolites of 4-Dimethylaminoazobenzene in Rat Bile and Influence of DAB Feeding on their Amounts
スポンサーリンク
概要
- 論文の詳細を見る
The biliary excretion of DAB metabolites was first examined by paper chromatography, colorimetry, and by other methods. Presence of a selectivity in rat liver was recognized such as the main excretion of DAB metabolites retaining the azo bond into the bile and seven kinds of DAB metabolites (AB, 4'-OS-DAB, 4'-OS-MAB, 4'-OS-AB, 4'-OG-MAB, 4'-OG-MAB, 4'-OG-AB) were identified. Second, influence of DAB feeding on the amount of these seven kinds of DAB metabolites was examined by the method of newly devised separatory determination using DEAE ion-exchanger and other methods. The most appropriate explanation for the results obtained was the promotion of hydroxylation in the first and middle stages of DAB feeding, although there were yet several problems.
- 公益社団法人日本薬学会の論文
- 1963-08-25
著者
-
石館 守三
Tokyo Biochemical Research Institute
-
鮫島 啓二郎
Tokyo Biochemical Research Institute
-
田村 善蔵
Faculty Of Pharmaceutical Sciences University Of Tokyo
-
鮫島 啓二郎
Faculty Of Pharmaceutical Sciences Josai University
関連論文
- 2-CARBOXY-1-HYDROXY-4-NAPHTHYLMETHYLDIMETHYLSULFONIUM CHLORIDE AS A NEW FLUORESCENT KOSHLAND REAGENT
- Fluorometric Determination of Biogenic Indole Compounds using Perchloric Acid
- Determination of Fluorescein and Fluorescein Monoglucuronide excreted in Urine
- Studies on the Metabolites of Fluorescein in Rabbit and Human Urine
- Simultaneous Determination of Multiple Enzyme Activities by High Performance Liquid Chromatography
- Supplemental Studies on Relationship between Structure and Spectrum of Fluorescein
- Spectrophotometric Determination of Bunte Salts as Bisulfite with Acidbleached Basic Fuchsine or N-(p-Dimethylaminophenyl)-1,4-naphthoquinoneimine after Reduction with Dithiothreitol
- Fluorescence Reaction of Bisulfite with Indophenol Blue and Its Application to Determination of Bisulfite
- A Simple Synthesis of Amino-containing Bunte Salts by the Reaction of Aminothiols with Chlorosulfonic Acid
- Spectrophotometric Determination of Bunte Salts
- Fluorometric Assay of Bisulfite
- The Production of Bisulfite from Pantetheine-S-sulfonic Acid by Bifidobacterium bifidum
- 2.増感培養法を用いたパントテン酸, ビオチンおよびニコチン酸の微生物学的超微量定量(JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY : 掲載論文要旨)
- Studies on the Metabolites in Urine and Feces of Rat after Oral Administration of Radioactive Pantethine
- Gas Chromatographic Analysis of Disaccharides. II. Analysis of Disaccharides in Human Body Fluids
- Mechanism of Utilization of Pantetheine-S-Sulfonic Acid by Bifidobacterium bifidum
- Gas Chromatography of Catecholamines and Related Compounds
- Relationship between Neurological Symptoms and Concentrations of Clioquinol in Serum and Nervous Systems of Beagle Dogs
- Gas Chromatography and Its Combination with Mass Spectrometry of Urinary Sugar Alcohols
- Fluorometric Analysis of Pyruvic Acid with 4'-Hydrazino-2-stilbazole
- A New Ultra-micro Microbioassay
- Behaviour of Plasma Sugars after Oral Administration of Lactose
- Gas Chromatographic Analysis of Disaccharides. I. Analysis of Disaccharides as Trimethylsilyl and Trifluoroacethyl Derivatives of Corresponding Alditols
- 7.Bioautographyの改良(ビタミンB研究委員会 第188回会議研究発表要旨)
- Fluorometric Determination of Pyridoxal-5-phosphate and Pyridoxal in Biological Materials. II. Specificity of the Method in Pyridoxal-5-phosphate Determination.
- Fluorometric Determination of Pyridoxal-5-phosphate and Pyridoxal in Biological Materials. I. Procedure and Application.
- Fluorometric Determination of Catecholamines on a Three-Phase Thin-Layer Plate
- Fluorometric Determination of Cyanide by the Reaction with Pyridoxal
- Reaction of Pyridoxal with Cyanide
- 4.Pyridoxal, Pyridoxal phosphateのKCNによる螢光定量(第8回ビタミンB_6定量小委員会研究発表要旨)
- 3.ピリドキサール, ピリドキサールリン酸のKCNによる螢光定量(第7回ビタミンB_6定量小委員会研究発表要旨)
- 3.ピリドキサールとKCN反応における生成物の検討(第6回ビタミンB_6定量小委員会研究発表要旨)
- 7.ピリドキサール, ピリドキサールリン酸の蛍光定量における生成物の検討(第5回ビタミンB_6定量小委員会研究発表要旨)
- 7.Apo-tryptophanase法の検討(ビタミンB_6測定小委員会第3回会議研究発表要旨)
- 9.Apo-tryptophanase法の検討(予報)(ビタミンB_6測定小委員会第2回会議研究発表要旨)
- Synthesis of Amino Sugar Containing Disaccharides. The Synthesis of Hyalobiuronic Acid and Chondrosine
- High-Performance Liquid Chromatographic Determination of L-3,4-Dihydroxyphenylalanine (L-DOPA) and Its Metabolites in the Urine of Patients with Parkinson's Disease, Control Patients and Normal Subjects after Oral Administration of L-DOPA
- Syntheses of ^N-Enriched Polyamines
- Metabolism of 4-Dimethylaminoazobenzene and Related Compounds. V. Quantitative Analysis of Biliary and Urinary Metabolites of 4-Dimethylaminoazobenzene in Rat.
- Presence of (±)-δ-(3,4-Dihydroxyphenyl)-γ-valerolactone in Human Urine
- Gas Chromatography of Copper (II) and Nickel (II) Chelates of Some β-Ketoimine Derivatives of 2,4-Pentanedione and Salicylaldehyde
- Metal Complexes of D-Glucosamine and its Derivatives. VII. Metal Complexes of D-Glucosaminic Acid
- Metal Complexes of D-Glucosamine and its Derivatives. VI. Determinations of Stability Constants of Copper Complexes of Methyl-β-D-glucosaminide and of 3,4,6-Tri-O-methyl-D-glucosamine by pH Titration Method
- Metal Complexes of D-Glucosamine and its Derivatives. V. Spectrophotometric Investigations on Copper (II), Nickel (II), and Cobalt (II) Complexes of D-Glucosamine and the Preparation of Glucosamine-copper Complex
- Metal Complexes of D-Glucosamine and its Derivatives. IV. Determinations of Stability and Equilibrium Constants of Metal Complexes of D-Glucosamine by pH Titration Method
- Metal Complexes of D-Glucosamine and its Derivatives. III. Determinations of Acid Dissociation Constants of D-Glucosamine and its Three O-Methyl Derivatives
- Semiquinone Radicals Generated from Catecholamines by Ultraviolet Irradiation
- 3-O-β-D-Glucopyranosiduronyl-D-glucaro-1,4-lactone
- Gas Chromatography of D-Glucaric Acid and Its Lactones, and Application to Measuring Their Transformation
- Synthesis of 5-Chloro-7-iodo-8-quinolinol (Chinoform) Glucuronide
- Studies on the Components of Clerodendron trichotomum THUNB. III. A New Glycoside, Acacetin-7-glucurono-(1→2)-glucuronide from the Leaves
- Selective Methanolysis of Lactone Rings in Some Acyl Carbohydrates
- Determination of Neutral and Amino Sugars in Glycoproteins by Gas Chromatography
- Serum Levels of 5-Chloro-7-iodo-8-quinolinol and Its Toxicity in Various Animals
- Hydrolysis of 5-Chloro-7-iodo-8-quinolinol Conjugates catalyzed by Metal Ions
- A Gas Chromatographic Determination Method of 5-Chloro-7-iodo-8-quinolinol and Its Conjugates in Biological Fluids
- Analysis of 5-Chloro-7-iodo-8-quinolinol Conjugates by High Performance Liquid Chromatography
- Assay of Arginine-esterase Activities by High Performance Liquid Chromatography
- A New Fluorometric Analysis of Dulcin using Sodium Nitrite. IV. Studies on the Reaction Mechanism
- Synthesis of 5-Chloro-7-iodo-8-quinolinol Sulfate
- A New Fluorometric Analysis of Dulcin using Sodium Nitrite. III. Structural Determination of the Fluorescent Compound by the Single Crystal X-Ray Diffraction Method
- A New Fluorometric Analysis of Dulcin using Sodium Nitrite. II. Isolation and Structural Investigation of the Fluorescent Compound
- Bifidus Factors in Carrot. I. Purification and Some Properties
- Simultaneous Determination of Urinary Uronic Acids and Saccharic Acids by Gas Chromatography
- Isolation and Structural Analysis of a Fluorescent Compound produced by the Reaction of Dulcin with Sodium Nitrite
- Selectivity of Utilization of Galactosyl-Oligosaccharides by Bifidobacteria
- Studies on the Glucaric Acid Pathway in the Metabolism of D-Glucuronic Acid in Mammals. III. Determination of D-Glucaric Acid in Serum, with Special Reference to Its Level after Administration of D-Glucuronolactone and D-Glucarolactones to Man
- Studies on the Glucaric Acid Pathway in the Metabolism of D-Glucuronic Acid in Mammals. II. Excretion of D-Glucaric Acid in Urine after Administration of Several Monosaccharides and Their Derivatives to Mammals
- Conversion of D-Mannuronolactone into D-Mannaric Acid in Mammalian Systems
- Gas Chromatography of Trifluoroacetyl Derivatives of Alditols and Trimethylsilyl Derivatives of Aldonolactones
- Determination of Vanilpyruvic Acid in Urine by High-Speed Liquid Chromatography
- An Improved Method for the Millon Reaction
- Mechanism of the Millon Reaction. II. The Crystal Structure of Pigment 1
- Studies on Carcinostatic Substances. XXXII. : Acquired Resistance of Yoshida Sarcoma by Treatment with Derivatives of Nitrogen Mustard.
- Studies on Carcinostatic Substances. XXVII. Anti-tumor Activity of 2-Chloroethylamine Derivatives on the in vitro-Cultured Yoshida Sarcoma Cells
- Studies on Carcinostatic Substances. XXII. Screening Method for Antimitotic Substance using the in vitro-Cultured Yoshida Sarcoma Cells.
- A Simpler Synthesis of D-Pantothenic Acid 4'-Phosphate
- Carcinostatic Methanesulfonic Acid Esters of Nitrogen Mustard Analogs
- Studies on Carcinostatic Substances. XXIX. 1,1-Bis(2-chloroethyl)-hydrazine and its Derivatives as Tumor-inhibiting Agent
- Studies on Carcinostatic Substances. XXVI. Preparation of Bis(2-chloroethyl)amine Derivatives and Related N-Oxides.
- Studies on Carcinostatic Substances. XXIV. Preparation of Diphenylphosphoric Acid Esters of N-Methyl-and N-Phenyl-bis(2-hydroxyethyl)amine and their Alkylating Activity.
- Studies on Carcinostatic Substances. XXIII. Correlation between Anti-tumor and leucopenia-inducing Effects of Alkylating Agents
- The Synthesis on N-Methyl[^C]-bis(2-chloroethyl)amine N-Oxide and its Excretion in the Urine of Dog.
- Reaction of Amide Homologs. III. α-Acylamidoalkylation of 2,4-Xylenol with Bisamides.
- Improved Synthesis of Decarboxylated S-Adenosylmethionine and Related Sulfonium Compounds
- Rearrangement Reaction of 7-Mercaptooxazolo[5,4-d]pyrimidine to 7-Hydroxythiazolo[5,4-d]pyrimidine
- Syntheses of Thiazolo-[5,4-d]pyrimidine Derivatives and Related Compounds.
- Inhibition of S-Adenosylmethionine Decarboxylase from Rat Liver by Synthetic Decarboxylated S-Adenosylmethionine and Its Analogs
- Preparation of Specific Antibody to 2,3-Trimethylene-4-quinazolone for the Immunoassay of Δ^1-Pyrroline
- Determination of Δ^1-Pyrroline as 2,3-Trimethylene-4-quinazolone
- 3-Ketoglucuronic Acid. II. Constitution and Chemical Properties of 3-Ketoglucuronic Acid
- 3-Ketoglucuronic Acid. I. Synthesis of 3-Ketoglucuronic Acid
- Synthesis of 3-Keto-D-glucuronic Acid
- A New Reductone derived from D-Glucuronolatone, 3-Keto-4,5-dideoxy-trans-4,5-dehydroglucuronic Acid
- A New Action of Anion Exchange Resins on the Lactone Ring of Some Carbohydrates
- Metabolism of 4-Dimethylaminoazobenzene and Related Compounds. III. Metabolites of 4-Dimethylaminoazobenzene in Rat Bile and Influence of DAB Feeding on their Amounts
- Studies on L-Gulonic Acid Derivatives. III. Synthesis of Benzyl 2,4,5,6-Tetra-O-benzyl-L-gulonate and Its Oxidation
- Studies on L-Gulonic Acid Derivatives. II. Benzoyl Migration in Derivatives of D-Glucitol
- A Probable Structure of the Bifidus Factor in Carrot Root
- Metabolites of p-Dimethylaminoazobenzene in Rat Bile