Syntheses of Thiazolo-[5,4-d]pyrimidine Derivatives and Related Compounds.
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概要
- 論文の詳細を見る
Heating of the sodium salt of 4-amino-5-acylamino-6-mercaptopyrimidine results in the formation of a purine derivative but its heating with dilute hydrochloric or sulfuric acid was found to give thiazolo[5,4-d]pyrimidine derivatives. 5-Amino-6-mercaptopyrimidine derivatives react with nitrile to form thiazolo[5,4-d]pyrimidine derivatives, while they react with monochloroacetic acid to form pyrimido[4,5-b][1,4]thiazine derivatives, and with nitrous acid to form thiadiazolo[5,4-d]pyrimidine derivatives.
- 公益社団法人日本薬学会の論文
- 1960-02-25
著者
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由岐 英剛
Faculty of Pharmaceutical Sciences, Osaka University
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石館 守三
Tokyo Biochemical Research Institute
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石館 守三
Faculty of Pharmaceutical Sciences, University of Tokyo
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由岐 英剛
Department of Clinical Chemistry, School of Pharmaceutical Science, Toho University
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由岐 英剛
Faculty Of Pharmaceutical Sciences Osaka University
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由岐 英剛
Department Of Clinical Chemistry School Of Pharmaceutical Science Toho University
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石館 守三
Faculty Of Pharmaceutical Sciences University Of Tokyo
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