Studies on Antiviral Agents. V. Synthesis and Antiviral Activity of N-Chloro Compounds.
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概要
- 論文の詳細を見る
N-chloro compounds were synthesized and their virus inactivating activity and probable mechanism of the action were investigated. It is likely that the N-chloro compounds oxidize the sulfhydryl groups of the viral protein coat to form disulfide, disulfoxide, and sulfinic acid resulting in inactivation of the virus. This action is nonspecific and irreversible, and is lost in the presence of serum proteins.
- 公益社団法人日本薬学会の論文
- 1967-08-25
著者
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東平 靖雄
Research Laboratories Chugai Pharmaceutical Co. Ltd.
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岸川 虎比古
Research Laboratories, Morishita Pharmaceutical Co., Ltd.
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佐野 文彦
Research Laboratories Chugai Pharmaceutical Co. Ltd.
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由岐 英剛
Department of Clinical Chemistry, School of Pharmaceutical Science, Toho University
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早川 繁
Research Laboratories Chugai Pharmaceutical Co. Ltd.
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由岐 英剛
Research Laboratories, Chugai Pharmaceutical Co., Ltd.
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鈴木 清吉
Research Laboratories, Chugai Pharmaceutical Co., Ltd.
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鈴木 清吉
Research Laboratories Chugai Pharmaceutical Co. Ltd.
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由岐 英剛
Faculty Of Pharmaceutical Sciences Osaka University
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由岐 英剛
Department Of Clinical Chemistry School Of Pharmaceutical Science Toho University
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岸川 虎比古
Research Laboratories Morishita Pharmaceutical Co. Ltd.
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