Studies on Carcinostatic Substances. XXVII. Anti-tumor Activity of 2-Chloroethylamine Derivatives on the in vitro-Cultured Yoshida Sarcoma Cells
スポンサーリンク
概要
- 論文の詳細を見る
More than 200 derivatives of 2-chloroethylamine were tested as to their anti-tumor effect on the in vitro-cultured Yoshida sarcoma cells. The results were discussed, especially in connection with conditions of activation of N-methyl-bis(2-chloroethyl)amine N-oxide by the tumor cells.
- 公益社団法人日本薬学会の論文
- 1960-05-25
著者
-
今村 博
Iatrochemical Institute Of Pharmacological Research Foundation
-
桜井 欽夫
Cancer Institute Japanese Foundation For Cancer Research
-
石館 守三
Tokyo Biochemical Research Institute
-
桜井 欽夫
Iatrochemical Institute Of The Pharmacological Research Foundation Tokyo
-
森脇 絢子
Iatrochemical Institute of Pharmacological Research Foundation
-
石舘 守三
Iatrochemical Institute of Pharmacological Research Foundation
関連論文
- Synthesis of Amino Sugar Containing Disaccharides. The Synthesis of Hyalobiuronic Acid and Chondrosine
- Metabolism of 4-Dimethylaminoazobenzene and Related Compounds. V. Quantitative Analysis of Biliary and Urinary Metabolites of 4-Dimethylaminoazobenzene in Rat.
- Bacteriostatic Activity of the Nitrogen Mustard N-Oxides against Escherichia coli
- N-Oxides of β-Chloroethylamine Derivatives.
- Studies on Carcinostatic Substances. XLI. Preparation of Azide Derivatives of 1,1-Bis (2-chloroethyl) hydrazine.
- The Effect of Anti-tumor Agents on the Dehydrogenase Activity of Tumors.
- Studies on the Glucaric Acid Pathway in the Metabolism of D-Glucuronic Acid in Mammals. III. Determination of D-Glucaric Acid in Serum, with Special Reference to Its Level after Administration of D-Glucuronolactone and D-Glucarolactones to Man
- Studies on the Glucaric Acid Pathway in the Metabolism of D-Glucuronic Acid in Mammals. II. Excretion of D-Glucaric Acid in Urine after Administration of Several Monosaccharides and Their Derivatives to Mammals
- Conversion of D-Mannuronolactone into D-Mannaric Acid in Mammalian Systems
- Studies on Carcinostatic Substances. XXXII. : Acquired Resistance of Yoshida Sarcoma by Treatment with Derivatives of Nitrogen Mustard.
- Studies on Carcinostatic Substances. XXVIII. Activation of the Derivatives of 2-Chloroethylamine with Latent Activity
- Studies on Carcinostatic Substances. XXVII. Anti-tumor Activity of 2-Chloroethylamine Derivatives on the in vitro-Cultured Yoshida Sarcoma Cells
- Studies on Carcinostatic Substances. XXII. Screening Method for Antimitotic Substance using the in vitro-Cultured Yoshida Sarcoma Cells.
- Studies on Carcinostatic Substances. XX. Studies on the Culture of Yoshida Sarcoma Cells in vitro.
- Synthesis and Evaluation of the Anticancer Activity of a New Series of Methanesulfonates
- Synthesis and Evaluation of the Anticancer Activity of Some Water Soluble Maleimide Derivatives
- Fatty Acid Components of Lipid Fractions of Yoshida Sarcoma and Rat Ascites Hepatomas
- Carcinostatic Activity of Several New Derivatives of Sulfonic Acid esters of Some Aminoglycols
- Preparation of Derivatives of Nitrogen Mustard having Structure of α-Amino Acid Amide
- Carcinostatic Methanesulfonic Acid Esters of Some Aminoglycols
- Carcinostatic Methanesulfonic Acid Esters of Nitrogen Mustard Analogs
- Studies on Carcinostatic Substances. XXXVII. Preparation of Derivatives of Nitrogen Mustard having Metal Chelate-forming Activity.
- Studies on Carcinostatic Substances. XXXVI. A New Type of Antitumor Derivatives of Nitrogen Mustard with Latent Activity.
- Studies on Carcinostatic Substances. XXXIV. Anti-tumor Activity of 2,2-Bis (2-chloroethyl) isoxazolidinium Chloride and Related Compounds.
- Studies on Carcinostatic Substances. XXX. Syntheses of Derivatives of Nitrogen Mustard related to Amino Acid.
- Paper Chromatographic Detection of Nitrogen Mustard
- Studies on Carcinostatic Substances. XXIX. 1,1-Bis(2-chloroethyl)-hydrazine and its Derivatives as Tumor-inhibiting Agent
- Studies on Carcinostatic Substances. XXVI. Preparation of Bis(2-chloroethyl)amine Derivatives and Related N-Oxides.
- Studies on Carcinostatic Substances. XXIV. Preparation of Diphenylphosphoric Acid Esters of N-Methyl-and N-Phenyl-bis(2-hydroxyethyl)amine and their Alkylating Activity.
- Studies on Carcinostatic Substances. XXIII. Correlation between Anti-tumor and leucopenia-inducing Effects of Alkylating Agents
- The Synthesis on N-Methyl[^C]-bis(2-chloroethyl)amine N-Oxide and its Excretion in the Urine of Dog.
- Reaction of Amide Homologs. III. α-Acylamidoalkylation of 2,4-Xylenol with Bisamides.
- Rearrangement Reaction of 7-Mercaptooxazolo[5,4-d]pyrimidine to 7-Hydroxythiazolo[5,4-d]pyrimidine
- Syntheses of Thiazolo-[5,4-d]pyrimidine Derivatives and Related Compounds.
- 3-Ketoglucuronic Acid. II. Constitution and Chemical Properties of 3-Ketoglucuronic Acid
- 3-Ketoglucuronic Acid. I. Synthesis of 3-Ketoglucuronic Acid
- Synthesis of 3-Keto-D-glucuronic Acid
- A New Reductone derived from D-Glucuronolatone, 3-Keto-4,5-dideoxy-trans-4,5-dehydroglucuronic Acid
- A New Action of Anion Exchange Resins on the Lactone Ring of Some Carbohydrates
- Metabolism of 4-Dimethylaminoazobenzene and Related Compounds. III. Metabolites of 4-Dimethylaminoazobenzene in Rat Bile and Influence of DAB Feeding on their Amounts
- Studies on L-Gulonic Acid Derivatives. III. Synthesis of Benzyl 2,4,5,6-Tetra-O-benzyl-L-gulonate and Its Oxidation
- Studies on L-Gulonic Acid Derivatives. II. Benzoyl Migration in Derivatives of D-Glucitol
- 1,1-Bis (2-chloroethyl) hydrazine and its Antitumor Activity
- Studies on Carcinostatic Substances. XIX. The Preparation and Properties of N, N'-Bis (2-chloroethyl)-N, N'-dimethylpolymethylenediamine N, N'-Dioxides.
- Studies on Carcinostatic Substances. XVIII. Anticancer Action of N, N'-Bis (2-chloroethyl)-N, N'-dimethylpolymethylenediamines.
- Studies on Cancerocidal Substances. XVII. Reaction of Nitrogen Mustard N-Oxides and Amino Acid.
- Studies on Cancerocidal Substances. XVI. Some Sulfonic Acid Esters as Anti-cancer Agents.
- Studies on Cancerocidal Substances. XV. Preparation of Some New Azo Derivatives of Bis (β-chloroethyl) amine.
- Studies on Carcinostatic Substances. XL. Application of Cell Counting Method to the Screening of Antitumor Substances using the in vitro-cultured Yoshida Sarcoma Cells.