Preparation of Derivatives of Nitrogen Mustard having Structure of α-Amino Acid Amide

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概要

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• A number of new amide derivatives of bis(2-chloroethyl)-DL-glycine and bis(2-chloroethyl)-DL-alanine were prepared and tested for their in vivo and in vitro antitumor activity against Yoshida Sarcoma, and chemical properties.

• 公益社団法人日本薬学会の論文
• 1965-05-25

著者

• 桜井 欽夫

  Cancer Institute Japanese Foundation For Cancer Research

• 松井 英一

  Tokyo Laboratory of the Yoshitomi Pharmaceutical Industries, Ltd.

関連論文

• Studies on Carcinostatic Substances. XLI. Preparation of Azide Derivatives of 1,1-Bis (2-chloroethyl) hydrazine.
• Studies on Carcinostatic Substances. XXXII. : Acquired Resistance of Yoshida Sarcoma by Treatment with Derivatives of Nitrogen Mustard.
• Studies on Carcinostatic Substances. XXVII. Anti-tumor Activity of 2-Chloroethylamine Derivatives on the in vitro-Cultured Yoshida Sarcoma Cells
• Studies on Carcinostatic Substances. XXII. Screening Method for Antimitotic Substance using the in vitro-Cultured Yoshida Sarcoma Cells.
• Studies on Carcinostatic Substances. XX. Studies on the Culture of Yoshida Sarcoma Cells in vitro.
• Synthesis and Evaluation of the Anticancer Activity of a New Series of Methanesulfonates
• Synthesis and Evaluation of the Anticancer Activity of Some Water Soluble Maleimide Derivatives
• Fatty Acid Components of Lipid Fractions of Yoshida Sarcoma and Rat Ascites Hepatomas
• Carcinostatic Activity of Several New Derivatives of Sulfonic Acid esters of Some Aminoglycols
• Preparation of Derivatives of Nitrogen Mustard having Structure of α-Amino Acid Amide
• Carcinostatic Methanesulfonic Acid Esters of Some Aminoglycols
• Carcinostatic Methanesulfonic Acid Esters of Nitrogen Mustard Analogs
• Studies on Carcinostatic Substances. XXXVII. Preparation of Derivatives of Nitrogen Mustard having Metal Chelate-forming Activity.
• Studies on Carcinostatic Substances. XXXVI. A New Type of Antitumor Derivatives of Nitrogen Mustard with Latent Activity.
• Studies on Carcinostatic Substances. XXXIV. Anti-tumor Activity of 2,2-Bis (2-chloroethyl) isoxazolidinium Chloride and Related Compounds.
• Studies on Carcinostatic Substances. XXX. Syntheses of Derivatives of Nitrogen Mustard related to Amino Acid.
• Paper Chromatographic Detection of Nitrogen Mustard
• Studies on Carcinostatic Substances. XXIX. 1,1-Bis(2-chloroethyl)-hydrazine and its Derivatives as Tumor-inhibiting Agent
• Studies on Carcinostatic Substances. XXVI. Preparation of Bis(2-chloroethyl)amine Derivatives and Related N-Oxides.
• Studies on Carcinostatic Substances. XXIV. Preparation of Diphenylphosphoric Acid Esters of N-Methyl-and N-Phenyl-bis(2-hydroxyethyl)amine and their Alkylating Activity.
• Studies on Carcinostatic Substances. XXIII. Correlation between Anti-tumor and leucopenia-inducing Effects of Alkylating Agents
• 1,1-Bis (2-chloroethyl) hydrazine and its Antitumor Activity
• Studies on Carcinostatic Substances. XIX. The Preparation and Properties of N, N'-Bis (2-chloroethyl)-N, N'-dimethylpolymethylenediamine N, N'-Dioxides.
• Studies on Carcinostatic Substances. XVIII. Anticancer Action of N, N'-Bis (2-chloroethyl)-N, N'-dimethylpolymethylenediamines.
• Studies on Cancerocidal Substances. XVII. Reaction of Nitrogen Mustard N-Oxides and Amino Acid.
• Studies on Cancerocidal Substances. XVI. Some Sulfonic Acid Esters as Anti-cancer Agents.
• Studies on Cancerocidal Substances. XV. Preparation of Some New Azo Derivatives of Bis (β-chloroethyl) amine.

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