Studies on Carcinostatic Substances. XXXVI. A New Type of Antitumor Derivatives of Nitrogen Mustard with Latent Activity.
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概要
- 論文の詳細を見る
Several derivatives of N-(2-substituted ethoxy)-2,2'-dichlorodiethylamine were prepared and tested for their latent antitumor activity against Yoshida sarcoma. Mode of activation of these compounds was also discussed.
- 公益社団法人日本薬学会の論文
- 1961-09-25
著者
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桜井 欽夫
Cancer Institute Japanese Foundation For Cancer Research
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桜井 欽夫
Iatrochemical Institute Of The Pharmacological Research Foundation Tokyo
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石舘 守三
Iatrochemical Institute of Pharmacological Research Foundation
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鳥越 政宏
Iatrochemical Institute of Pharmacological Research Foundation
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石舘 守三
Faculty Of Pharmaceutical Sciences Hokkaido University
関連論文
- Bacteriostatic Activity of the Nitrogen Mustard N-Oxides against Escherichia coli
- N-Oxides of β-Chloroethylamine Derivatives.
- Studies on Carcinostatic Substances. XLI. Preparation of Azide Derivatives of 1,1-Bis (2-chloroethyl) hydrazine.
- The Effect of Anti-tumor Agents on the Dehydrogenase Activity of Tumors.
- Studies on Carcinostatic Substances. XXXII. : Acquired Resistance of Yoshida Sarcoma by Treatment with Derivatives of Nitrogen Mustard.
- Studies on Carcinostatic Substances. XXVII. Anti-tumor Activity of 2-Chloroethylamine Derivatives on the in vitro-Cultured Yoshida Sarcoma Cells
- Studies on Carcinostatic Substances. XXII. Screening Method for Antimitotic Substance using the in vitro-Cultured Yoshida Sarcoma Cells.
- Studies on Carcinostatic Substances. XX. Studies on the Culture of Yoshida Sarcoma Cells in vitro.
- Synthesis and Evaluation of the Anticancer Activity of a New Series of Methanesulfonates
- Synthesis and Evaluation of the Anticancer Activity of Some Water Soluble Maleimide Derivatives
- Fatty Acid Components of Lipid Fractions of Yoshida Sarcoma and Rat Ascites Hepatomas
- Carcinostatic Activity of Several New Derivatives of Sulfonic Acid esters of Some Aminoglycols
- Preparation of Derivatives of Nitrogen Mustard having Structure of α-Amino Acid Amide
- Carcinostatic Methanesulfonic Acid Esters of Some Aminoglycols
- Carcinostatic Methanesulfonic Acid Esters of Nitrogen Mustard Analogs
- Studies on Carcinostatic Substances. XXXVII. Preparation of Derivatives of Nitrogen Mustard having Metal Chelate-forming Activity.
- Studies on Carcinostatic Substances. XXXVI. A New Type of Antitumor Derivatives of Nitrogen Mustard with Latent Activity.
- Studies on Carcinostatic Substances. XXXIV. Anti-tumor Activity of 2,2-Bis (2-chloroethyl) isoxazolidinium Chloride and Related Compounds.
- Studies on Carcinostatic Substances. XXX. Syntheses of Derivatives of Nitrogen Mustard related to Amino Acid.
- Paper Chromatographic Detection of Nitrogen Mustard
- Studies on Carcinostatic Substances. XXIX. 1,1-Bis(2-chloroethyl)-hydrazine and its Derivatives as Tumor-inhibiting Agent
- Studies on Carcinostatic Substances. XXVI. Preparation of Bis(2-chloroethyl)amine Derivatives and Related N-Oxides.
- Studies on Carcinostatic Substances. XXIV. Preparation of Diphenylphosphoric Acid Esters of N-Methyl-and N-Phenyl-bis(2-hydroxyethyl)amine and their Alkylating Activity.
- Studies on Carcinostatic Substances. XXIII. Correlation between Anti-tumor and leucopenia-inducing Effects of Alkylating Agents
- Reaction of Nitrogen Mustard with the Components of Ribonucleic Acid.
- Metabolism of 4-Dimethylaminoazobenzene and Related Compounds. II. Metabolites of 4-Dimethylaminoazobenzene and 4-Aminoazobenzene in Rat Urine.
- The Metabolism of p-Dimethylaminoazobenzene and Related Compounds. I. Metabolites of p-Dimethylaminoazobenzene in Dog Urine.
- A New Reductone derived from D-Gluculonolactone by Alkali. II. Further Studies on the Properties of the Reductone
- A New Reductone derived from D-Glucuronolactone by Alkali. I. Isolation of 3-Keto-4,5-dideoxy-trans-4,5-dehydro-glucuronic Acid
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- Reaction of Cysteine with Nitrogen Mustards and their N-oxides.
- Studies on Carcinostatic Substances. XXXV. Chemical and Antitumor Properties of Quaternary Derivatives of N-Alkoxy-2,2'-dichlorodiethylamine.
- Arylamine N-Glucuronide and its Structure.
- Synthesis of Methyl 1,2-O-Isopropylidene-3-oxo-5-O-acetyl-D-glucofuranuronate
- 1,1-Bis (2-chloroethyl) hydrazine and its Antitumor Activity
- Studies on Carcinostatic Substances. XIX. The Preparation and Properties of N, N'-Bis (2-chloroethyl)-N, N'-dimethylpolymethylenediamine N, N'-Dioxides.
- Studies on Carcinostatic Substances. XVIII. Anticancer Action of N, N'-Bis (2-chloroethyl)-N, N'-dimethylpolymethylenediamines.
- Studies on Cancerocidal Substances. XVII. Reaction of Nitrogen Mustard N-Oxides and Amino Acid.
- Studies on Cancerocidal Substances. XVI. Some Sulfonic Acid Esters as Anti-cancer Agents.
- Studies on Cancerocidal Substances. XV. Preparation of Some New Azo Derivatives of Bis (β-chloroethyl) amine.
- Metabolites of p-Dimethylaminoazobenzene in Rat Bile
- Oxidative N-Demethylation of Aminoazo Compounds by Model System. I. Oxidation of 4-N-Dimethylaminoazobenzene by Some Systems.